2000～2002年我院常见细菌的分离率与耐药监测  

Isolation and antibiotic resistant monitoring of bacteria isolated from our hospital from the year 2000 to 2002

作　　者：过孝静[1] 康梅[1] 陈知行[1] 陈文昭[1] 吕晓菊[1] 

机构地区：[1]四川大学华西医院临床微生物实验室,成都610041

出　　处：《中国抗生素杂志》2004年第4期223-225,共3页Chinese Journal of Antibiotics

摘　　要：目的　了解 2 0 0 0～ 2 0 0 2年常见菌的分布与耐药状况。方法　采用上海新和公司实验室信息管理系统软件对分离的菌株和药敏试验结果进行分析。结果　大肠埃希氏菌、铜绿假单胞菌、不动杆菌、肺炎克雷伯氏菌、金黄色葡萄球菌分离率占前五位 ,且有逐年增加趋势。大肠埃希氏菌对亚胺培南、头孢西丁、头孢他啶的耐药率在 30 %以下 ,铜绿假单胞菌对哌拉西林、头孢他啶、头孢吡肟、阿米卡星的耐药率在 30 %以下 ,不动杆菌对亚胺培南的耐药率低于 11% ,其余抗生素耐药率均高于 30 % ;金黄色葡萄球菌对复方磺胺甲口恶唑的耐药率在 10 %以下 ,对万古霉素耐药率为零 ,对其余抗生素的耐药率波动较大 ,特别是 2 0 0 2年的耐药率显著上升。结论　动态了解病原菌的分离率 ,熟悉抗生素的敏感性和耐药率有助于临床医生合理应用抗生素 ,制定正确的抗感染方案。Object To investgate the distribution and drug resistance of common bacteria isolated from our hospital in the year 2000～2003. Methods Analysed the isolated strains and drug susceptibility test results by XinHe Lab Information system. Results The most prevalent isolated strains are E.coli, Pseudomonas aeruginosa, Acinetobacter, Klebsielia pneumoniae and Staphylococcus aureus , which are increasing year by year. The resistance rate of E.coli to imipenem, cefoxitin, and ceftazidime was below 30%; while Pseudomonas aeruginosa to piperacillin and amikacin was below 30%; Acinetobacter to imipenem was below 11%; Staphylococcus aureus to SMZ was below 11%. All Staphylococcus aureus were susceptiple to vancomycin. Conclusion By dynamic understanding the distribution of isolates and drug susceptibility test results of different bacteria could help doctors to decide the rational antimicrobial therapy.

关 键 词：病原菌 分离率 耐药率 

分 类 号：R378[医药卫生—病原生物学]