螺旋CT评价冠状动脉钙化积分和预测冠心病事件的可靠性  

Reliability of spiral computed tomography in evaluating the coronary artery calcification and predicting occurrence of coronary heart disease events

作　　者：王汐[1] 刘白鹭[2] 刘明宇[1] 朱红[1] 笠井贵久男 

机构地区：[1]哈尔滨医科大学附属第二医院老年病科,黑龙江省哈尔滨市150086 [2]哈尔滨医科大学附属第二医院CT室,黑龙江省哈尔滨市150086 [3]日本独协医科大学内分泌代谢内科

出　　处：《中国临床康复》2004年第12期2240-2241,共2页Chinese Journal of Clinical Rehabilitation

基　　金：日本独协医科大学基金资助(156020807)~~

摘　　要：目的:应用螺旋CT评价冠状动脉钙化积分和预测冠心病事件发生的可能性。方法:既往有冠心病史或经心电图负荷试验和/或冠状动脉造影,临床确诊为冠心病患者87例(冠心病组)和非冠心病患者125例(对照组),分别进行螺旋CT检查,记录年龄、钙化率、钙化积分、冠状动脉钙化的部位及支数。结果:两组均随年龄的增长钙化率逐渐增高,70岁以上钙化率达90%以上。冠心病组与对照组的冠状动脉钙化积分有显著性差异(t=-26.83～-9.93,P<0.01),也随年龄的增长而增加,钙化血管支数与钙化积分呈正相关,以左前降支钙化发生率最高,为72%。结论:应用螺旋CT检测冠状动脉钙化,对可疑冠心病患者,提供早期诊断的依据。对冠状动脉狭窄程度的追踪观察是一种可靠、无创、可反复进行的有效方法。AIM: To investigate the diagnostic value of coronary artery calcification scoring(CACS) detected by spiral computed tomography(CT) for coronary heart disease(CHD). METHODS: Spiral CT was performed for 87 patients with CHD(CHD group,having a history of CHD or affirmed by electrocardiogram stress test and/or coronary angiography) and 125 subjects without CHD(control group),respectively.Age,calcification incidence,calcification scoring,place and number of coronary artery calcification were recorded and analyzed. RESULTS: The CAC incidences increased with age in both groups. Calcification incidence was above 90%in those above 70 years old. The CACS in the CHD group was significantly different from that in the control group(t=-26.83--9.93,P< 0.01), and increased significantly with age in both groups.There was a positive relation between the number of vessels with calcification and the coronary calcification scoring, and the CAC incidence of left anterior descending coronary artery branch(LAD) was the highest(72%) among all coronary arteries.The detection of CAC by spiral CT provides evidence for the early diagnosis of CHD in patients suspected with CHD. It is a reliable, non invasive and reproducible method to track the progression of the extent of coronary stricture.

关 键 词：螺旋CT检查 冠状动脉钙化 钙化积分 预测 冠心病 诊断 

分 类 号：R541.4[医药卫生—心血管疾病] R816.2[医药卫生—内科学]