CR1在红细胞免疫中的研究进展  

The study improvement of complement receptor type 1 in the function of red cell immune adhesion

作　　者：黄清水[1] 任春锋[1] 杨红英[1] 

机构地区：[1]昆明医学院第二附属医院,云南昆明650101

出　　处：《井冈山医专学报》2004年第2期12-15,共4页Journal of Jinggangshan Medical College

摘　　要：目的总结Ⅰ型补体受体(CR1,CD35)在红细胞免疫中的研究进展。方法通过阅读有关文献,了解红细胞CR1在红细胞免疫研究中的地位。结果CR1分子有其特定的编码基因、分子结构、生物学特性,广泛参与体内免疫复合物(IC)的清除。结论CR1是红细胞执行免疫功能的主要分子基础。Objective:We summarize the studies of complement receptor type 1(CR1)in the function of red cell immune adhesion(RCIA).Method:To investigate the role of CR1 on erythrocytes in the function of RCIA through studying the involved articles.Result:In addition to the special coding sequence,molecular structure and biological specificity of the CR1,It play a important role in the clearance of circulating immune complexes from the circulation to the reticuloendothelial system,including the liver and spleen.Conclusion:CR1 is one of the molecular basis of the function of RCIA.

关 键 词：红细胞 免疫功能 I型补体受体(CR1) 

分 类 号：R392.11[医药卫生—免疫学]