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机构地区:[1]广东医学院附属医院麻醉科,广东湛江524001
出 处:《实用医药杂志》2004年第3期197-198,共2页Practical Journal of Medicine & Pharmacy
摘 要:目的观察控制性降压在经尿道前列腺电切术(TURP)中的安全性有效性。方法应用硝酸甘油在TURP时行控制性降压,与对照组相比测定两组患者出血量、手术时间、冲洗液量、PaO2、PaCO2、Na+、K+、Cl-、pH等指标,分析比较两组临床资料与指标。结果控制性降压组TURP时出血量、手术时间、冲洗液量等较对照组有明显减少,两组差异有非常显著性意义(P<0.01),两组PaO2、PaCO2、K+、Na+、Cl-、pH无明显差异(P>0.05)。结论TURP时采用硝酸甘油控制性降压可有效减少出血、减少冲洗液量、缩短手术时间,不影响内环境变化,此方法简单、安全、有效,值得临床推广应用。Objective To observe the safety and effectiveness of controlled hypotension in transurethral resection of the prostate(TURP). Methods The 40 cases of benign prostatic hyperplasia (BPH) were randomized into two groups: 20 cases were injected with nitroglycerinum to make controlled hypotension in TURP as experiment group; other 20 cases as controlled group. The volume of rinsings, blood lossing, operation time, as well PaO2, PaCO2, Na+, K+, Cl-, pH and CVP were recorded during the operation in both groups. As comparative study of clinical data was made between two groups. Results The volume of rinsings, blood lossing and operation time were much less in experiment group than that in controlled group. There were significant differences between two groups(P<0.01). There were no significant difference between two groups in PaO2, PaCO2, K+, Na+, Cl-, pH and CVP. Conclusion Injecting nitroglycerinum to controlled hypotension in TURP can effectively reduce the volume of rinsings, blood lossing and operation time. This technique is safe, simple & and feasible, and can be adaptable for clinical application.
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