29株偶然分支杆菌耐药性观察  

The drug resistance results of 29 strains Mycobacterium fortuitum

作　　者：邱志强[1] 梁庆福[1] 王玮[1] 刘坦业[1] 池细俤[2] 高世华[2] 林蓉金[2] 

机构地区：[1]福建省结核病防治所,福州350007 [2]福建省南平市第一医院,南平353000

出　　处：《中国防痨杂志》2004年第1期45-47,共3页Chinese Journal of Antituberculosis

摘　　要：目的　了解偶然分支杆菌耐药性。方法　确定的 2 9株偶然分支杆菌临床分离株 ,进行主要抗结核药物作耐药性测定。结果　对氧氟沙星、左氧氟沙星敏感 ,对 6种抗结核分支杆菌药单一药敏试验均耐药。 2～ 3种药物联合药敏试验显示低浓度耐药 ,高浓度敏感。结论　建议采用敏感抗生素联合有协同作用的抗结核药进行化疗 ,可望取得临床治愈效果。Objective To determine the drug resistance on Mycobacterium fortuitum .Methods 29 strains M.fortuitum of clinical isolates had been identified by conventional and molecular biological identification methods were uesed for susceptibility tests to the main anti-tuberculosis drugs.Results The isolates were susceptible to OFLX and LVFX,resisted to all single anti-tuberculosis drug;The results of malti-drugs susceptibility test showed that the isolates resistant to two or three anti-tuberculosis drugs at the low concentration but susceptible at the high concentrat .Conclusion It will be possible toget higher cure rate,if the clinical cases should been treated with susceptible antibiotics in combination with anti-tuberculosis drugs in synergism.

关 键 词：分支杆菌 耐药性 药物耐受性 药敏试验 菌种 

分 类 号：R446.5[医药卫生—诊断学]