SARS病毒抗体产生与中医证候特征相关性分析  

Pertinence of the Characteristic of TCM Clinic Presentations in Convalescence of SARS and the Antibody of SARS Virus

作　　者：宋庆桥[1] 齐文升[1] 边永君[1] 

机构地区：[1]中国中医研究院广安门医院,北京100053

出　　处：《中国中医药信息杂志》2004年第3期199-201,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：北京市中医药管理局资助课题(京中科SARS-13)

摘　　要：目的 观察分析SARS病毒抗体的产生与否对中医辨证论治的影响。方法 采用酶联免疫吸附法(ELISA)检测恢复期患者血清抗SARS病毒IgG,观察病毒抗体的产生与否在中医辨证上的区别;中药系列方治疗3周后,分析病毒抗体的产生与否对中药治疗的影响以及疗后中医证型分布特征。结果 恢复期气阴两虚证患者抗体产生的比例较高,但未形成统计学差异(P=0.633);治疗后,未经过中药干预者结果同疗前,经过中药干预者辨证为正常和气阴两虚者抗体阳性比例较高,但无统计学差异(P=0.083);另外,未兼挟湿邪、热邪者多见抗体阳性(P=0.006;P=0.048),有显著的统计学差异。结论 抗体的产生代表了正气的恢复过程,机体阴阳平衡、不兼挟余邪者,抗体阳性率较高,中药干预效果较好。Objective To discuss the relationship between the characteristic of TCM clinical presentations and the production of SARS virus antibody. Method Examine the IgG of SARS virus in SARS convalescence patient's serum by ELISA method to discuss the relationship between the characteristic of TCM clinical presentations and the production of SARS virus antibody. After 3 weeks therapy by TCM, we observed if the production of antibody have effective in TCM therapy and the distributing of the characteristic of TCM clinical presentations. Results Before treatment, the rate of produce antibody in deficiency of Qi and Yin was higher than other models but not remarkable (P=0.633). After treatment, the rate was same as before in the group without TCM therapy. In the group with TCM therapy, the rates are higher in models of normal and deficiency of Qi and Yin, but is still not remarkable (P=0.083). The antibody positive were more appearance which without damp and heat, which are remarkable (P=0.006 and P=0.048). Conclution The production of antibody means the process of resume. The rate of antibody production is higher in the patients who is equiangular in Yin and Yang or without remaining irregular, and the effective was better by TCM therapy.

关 键 词：SARS病毒抗体 中医证候 相关性 严重急性呼吸系统综合征 气阴两虚证 中医药疗法 

分 类 号：R373.1[医药卫生—病原生物学] R259.631[医药卫生—基础医学]