动态增强MRI对软组织肿块良、恶性的鉴别诊断价值  

The value of dynamic contrast-enhanced MR imaging in differentiating benign and malignant soft-tissue masses

作　　者：高莉[1] 蒋学祥[1] 周元春[1] 高玉洁[1] 肖江喜[1] 

机构地区：[1]北京大学第一医院放射科,100034

出　　处：《中华放射学杂志》2003年第3期264-267,共4页Chinese Journal of Radiology

摘　　要：目的　评价动态增强MRI对软组织肿块和肿瘤样病变的良、恶性的鉴别价值。方法对 3 0例经病理证实的软组织肿块进行动态增强扫描 ,其中恶性肿瘤 11例 ,良性肿块 19例。将感兴趣区 (ROI)的信号强度绘制成时间 信号强度曲线 (TIC) ,并分别计算其 0 5min斜率值。结果　 3 0例软组织肿块的TIC分为 3型 ,12例表现为Ⅰ型曲线 ,其中 10例为恶性肿瘤 ,2例为良性肿瘤 ;12例表现为Ⅱ型曲线 ,其中 11例为良性肿块 ,1例为恶性肿瘤 ;6例表现为Ⅲ型曲线 ,均为良性肿块。 11例恶性肿瘤中 ,10例病变的 0 5min斜率值大于 0 0 0 5 7;19例良性肿块中 ,17例 0 5min斜率小于 0 0 0 5 7;良、恶性肿瘤的TIC斜率值之间存在显著性差异 ,Logistic回归分析病变良、恶性和斜率值有相关性。以 0 5min斜率值 0 0 0 5 7作为鉴别肿块良恶性的阈值 ,判断肿块良、恶性的敏感性为 90 9% ,特异性为 89 4% ,阳性预测值为 83 3 % ,阴性预测值为 94 4%。结论　动态增强MRI可以较准确地预测肿瘤病变的良。Objective To assess the diagnostic value of dynamic contrast enhanced MR imaging in predicting the efficacy of distinguishing benign from malignant soft tissue tumor Methods Dynamic contrast enhanced MR imaging was performed in 30 patients with pathologically confirmed soft tissue tumors The MR signal intensity of the ROI was plotted The slope value of the time intensity curve was analyzed Results There was significant difference between the slope value of benign and malignant lesions Based on the slope value of half minute, differentiation of benign from malignant lesions was possible with 90 9% of the sensitivity, 89 4% of the specificity, 83 3% of the positive predictive value and 94 4% of the negative predictive value Conclusion Dynamic contrast enhance MR imaging can correctly predict benignity or malignance of soft tissue tumors

关 键 词：动态增强 MRI 软组织肿块 鉴别诊断 肿瘤样病变 软组织肿瘤 

分 类 号：R445.2[医药卫生—影像医学与核医学]