黑面神化学成分的研究(英文)  

Study on Chemical Constituents from Breynia fruticosa

作　　者：浮光苗[1] 余伯阳[1] 朱丹妮[1] 

机构地区：[1]中国药科大学中药复方研究室,南京210038

出　　处：《中国药科大学学报》2004年第2期114-116,共3页Journal of China Pharmaceutical University

摘　　要：目的 :研究中草药黑面神的化学成分。方法 :黑面神嫩枝和叶子用 95 %乙醇回流提取 ,提取物分别用氯仿、正丁醇萃取 ,将氯仿部位和正丁醇部位分别进行硅胶柱层析 ,其中正丁醇部位的化合物采用重结晶、SephadexLH 2 0柱层析方法进行纯化 ;通过IR、UV、MS、1HNMR和13 CNMR等波谱解析方法以及和化合物标准品对比的方法进行结构鉴定。结果 :从黑面神氯仿部位分离得到了 8个化合物 ,分别鉴定为正丁基 β D 吡喃果糖苷 (n butyl β D fructopyranoside ,Ⅰ )、乙基 β D 吡喃果糖苷 (ethyl β D fructopyranoside ,Ⅱ )、阿魏酸二十四烷醇酯 (tetracosylferulate ,Ⅲ )、β 谷甾醇 ( β sitosterol,Ⅳ )、正三十二烷醇 (n dotriacontanol,Ⅴ )、胡萝卜苷 (daucosterol,Ⅵ )、熊果苷 (arbutin ,Ⅶ )和 ( ) 表儿茶素 ( ( ) epicatechin ,Ⅷ )。结论AIM:To investigate the chemical constituents from the aerial parts of Breynia fruticosa. . METHOD: Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chemical evidence and spectral methods. RESULT:Eight compounds were obtained and identified by spectroscopic methods and compared with authentic samples as n butyl β D fructopyranoside,ethyl β D fructopyranoside,tetracosylferulate,β sitosterol, n dotriacontanol,daucosterol,arbutin and ( ) epicatechin. CONCLUSION:All compounds were firstly isolated from Breynia fruticosa (L.)Hook. f.

关 键 词：黑面神 大戟科 化学成分 分离 鉴定 

分 类 号：R284.2[医药卫生—中药学]