婴幼儿腹泻抗菌药物的使用与分析  

Analysis of antimicrobial usage in children with acute diarrhea

作　　者：邓静[1] 于四景[2] 林修寿[1] 

机构地区：[1]中南大学公共卫生学院,湖南长沙410078 [2]湖南省儿童医院,湖南长沙410007

出　　处：《中国感染控制杂志》2004年第2期143-145,共3页Chinese Journal of Infection Control

摘　　要：目的　了解儿童腹泻治疗中抗菌药物的使用情况 ,促进临床合理用药。方法　自行设计调查表收集某儿童医院腹泻患儿的临床用药情况和病原学检查结果 ,应用SPSS软件进行分析。结果　腹泻患儿抗菌药物使用率为 76 .94 % ,其中 ,第 3代头孢菌素 (5 6 .39% )和呋喃唑酮 (4 1 .1 1 % )的使用率最高 ;在使用抗菌药物的 2 77例患儿中 ,使用 1种抗菌药物者 1 0 1例 (36 .4 6 % ) ,2种及以上者 1 76例 (6 3.5 4 % ) ,参考病原学检查及药敏试验选择抗菌药物者 4 3例 (1 5 .5 2 % )。大部分细菌性痢疾采用 2种抗菌药物治疗 (73.89% ) ,非痢疾的其他感染性腹泻中 ,抗菌药物使用率为 5 9.1 1 % ,以单种抗菌药物为主 (占 4 9.75 % )。结论　在对儿童腹泻的治疗中 ,抗菌药物的使用仍然很普遍 。Objective To study the antimicrobial usage in children with acute diarrhea, and to promote the rational clinical antimicrobial application. Methods Questionnaires for the investigation of clinical antimicrobial use and pathogenic exam results were designed, all data were entered into computer and analysed by SPSS software. Results The usage rate of antimicrobial agents in children with diarrhea was 76.94%, the third generation of cephalosporins was the most common used agents (56.39%) and followed by furanzolidone (41.11%). Among 277 patients who had received antimicrobial agents therapy, 101 patients (36.46%) used only one kind of antimicrobial agents, 176 (63.54%) used at least two kinds of antimicrobial agents, 43 (15.52%) children received their therapy according to the results of pathogenic and antimicrobial susceptibility tests, most bacterial dysentery was treated by two kinds of antimicrobial agents (73.89%), 59.11% of children with non bacterial diarrhea received antimicrobial agents therapy, and the majority (49.75%) were treated by single agents. Conclusion The application of antimicrobial agents in children with diarrhea is prevalent, it is necessary to pay attention to the rational use of antimicrobial agents.

关 键 词：婴幼儿 腹泻 抗菌药物 病原学 药敏试验 

分 类 号：R723.11[医药卫生—儿科] R978.1[医药卫生—临床医学]