硒对儿童桥本甲状腺炎的影响  

Effects of Selenium on Children with Hashmoto's Thyrolditis

作　　者：王栋钢[1] 雷培芸[1] 杨咏梅[2] 杨渝生[1] 尹僖[1] 

机构地区：[1]重庆医科大学儿童医院,重庆400014 [2]重庆市巴南区第二人民医院,重庆400054

出　　处：《广东微量元素科学》2004年第2期34-36,共3页Trace Elements Science

摘　　要：为探讨硒对儿童桥木甲状腺炎的干预效果,采用双盲前瞻性随机对照试验观察了亚硒酸钠对桥本甲状腺炎患儿甲状腺球蛋白抗体(TGA) 和甲状腺微粒体抗体(TMA)的影响。结果表明,亚硒酸钠治疗组治疗后,TMA显著下降(P<0.01),而TGA没有差异(P>0.05)。提示硒可降低儿童桥本甲状腺炎TMA的质量分数。To study the effects of selenium on children with hashmoto's thyroiditis, adouble-blinded, place- bo-controlled, prospective study were performed in patients [n = 50; mean age (9.7±1.6) yr] with au- toimmune thyroiditis and thyroid microsomic antibody(TMA) and Tg antibodies (TGA). The patients were randomly divided into 2 groups. 25 patients received 200 mg sodium selenite orally for 3 months, and the oth- ers received placebo. The result showed that after treatment with sodium selenite, the level of TGA had no dif- ference between sodium selenite and placebo (P>0.05), but the difference of TMA was significant (P< 0.01). It concluded sodium selenite could significantly decrease the level of TMA of hashmoto's thyroiditis.

关 键 词：硒 桥本甲状腺炎 甲状腺微粒体抗体 

分 类 号：O613.52[理学—无机化学] R581.4[理学—化学]