低分子肝素并噻氯匹定在激光心肌血管重建术中的应用  

THE COMBINATION USE OF LOW MOLECULAR WEIGHT HEPARIN AND TIDOPIDINE HYDROCLORIDE FOR TRANSMYOCARDIAL LASER REVASCULARIZATION

作　　者：王刚[1] 王均志[1] 范作文[1] 黄从新[2] 

机构地区：[1]青岛市海慈医院心内科,山东青岛266033 [2]湖北省人民医院

出　　处：《齐鲁医学杂志》2004年第1期46-47,共2页Medical Journal of Qilu

摘　　要：①目的　观察激光心肌血管重建术 (TMLR)后联合应用低分子肝素及噻氯匹定对临床疗效的影响。②方法　 2 8例行TMLR术后病人中 ,18例联合应用低分子肝素与噻氯匹定 ,10例应用肠溶阿司匹林 ,观察两组病人心绞痛缓解程度、心功能改善状况。③结果　TMLR后 6个月 ,2 8例病人心绞痛及心功能均得到显著改善 ,但应用低分子肝素与噻氯匹定者更明显 (uc=5 .98～ 14 .33,P均 <0 .0 5 )。④结论　TMLR术后使用低分子肝素及噻氯匹定能够有效提高TMLR临床疗效 ,改善预后。ObjectiveTo observe the effect of low molecular weight heparin and tidopidine hydrocloride on transmyocardial laser revascularization (TMLR). MethodsTwenty-eight patients after receiving TMLR were investigated. Eighteen cases were given low molecular weight heparin and tidopidine hydrocloride, the other 10 cases took enteric-coated aspirin. The remission of angina and improvement of heart function were evaluated for both groups.ResultsAll the patients improved greatly in angina pectoris and heart function, but the patients receiving low molecular weight heparin and tidopidine hydrocloride improved more evidently (u c=5.98-14.33,P<0.05).ConclusionPost-TMLR use of combined low molecular weight heparin and tidopidine hydrocloride can improve clinical efficacy and prognosis. [

关 键 词：低分子肝素 噻氯匹定 激光 心肌血管重建术 

分 类 号：R654[医药卫生—外科学]