肺炎并发心力衰竭病儿血浆脑钠素水平的变化  

CHANGE OF BRAIN NATRIURETIC PEPTIDE IN CHILDREN WITH PNEUMONIA AND HEART FAILURE

作　　者：常红[1] 盛学岐[1] 范希文[1] 蒋玉红[1] 王文棣[1] 

机构地区：[1]青岛市妇女儿童医疗保健中心小儿内科,山东青岛266011

出　　处：《齐鲁医学杂志》2004年第1期53-54,共2页Medical Journal of Qilu

摘　　要：①目的　探讨肺炎并发心力衰竭 (心衰 )病儿血浆脑钠素 (BNP)水平的变化。②方法　选取肺炎并发心衰病儿 34例作为观察组 ,选择肺炎病儿 4 0例、健康儿童 4 0例作为对照组 ,采用酶联免疫吸附法检测血浆BNP水平。③结果　肺炎心衰病儿心衰各期血浆BNP水平明显高于对照组 (d =92 .4～ 136 .7,P <0 .0 0 1) ;肺炎心衰病儿心衰期血浆BNP水平与心衰早期及恢复期比较 ,差异有显著性 (d =36 .1、4 1.9,P <0 .0 5 )。④结论　肺炎心衰病儿血浆BNP水平明显升高且与心衰分期有关。ObjectiveTo study the serum level of brain natriuretic peptide (BNP) in children with pneumonia and heart failure (HF) . MethodsThe serum levels of BNP were determined in 34 children with HF, 40 with pneumonia and 40 healthy ones by enzyme-linked immunoabsorbent assay.ResultsThe BNP serum level was markedly higher in the children with HF than in the controls (d=92.4-136.7,P<0.001). The BNP level was significantly increased at HF compared with that at the early stage and recovery (d=36.1,41.9,P<0.05). ConclusionThe BNP serum levels are significantly high in children with HF, which is closely related to the stage of heart failure. [

关 键 词：肺炎 心力衰竭 血浆脑钠素 儿童 

分 类 号：R725.631[医药卫生—儿科] R725.416[医药卫生—临床医学]