ACA结合ANA、ENA在不同流产类型中的表达  

Expressions of ACA Combined with ANA and ENA in Different Types of Abortion

作　　者：戴芙蓉[1] 伍招娣[1] 彭国庆[1] 裴琛琳[1] 

机构地区：[1]中南大学湘雅医院妇产科,湖南长沙410008

出　　处：《医学临床研究》2004年第3期242-244,共3页Journal of Clinical Research

摘　　要：【目的】探讨ACA、ANA、ENA和流产类型的关系和临床意义。【方法】定性测定 6 8例先兆流产、6 5例复发性流产、2 2例难免流产、2 6例过期流产患者静脉血清中的ACA、ANA、ENA。【结果】ACA在不同类型流产中的阳性率分布差异有显著性 (P <0 .0 5 )。ANA和ENA在不同类型流产中的阳性率分布差异无显著性 (P >0 .0 5 )。【结论】ACA和复发性流产的关系最为密切 ,其次依次为难免流产、过期流产和先兆流产。尽早发现和治疗ACA阳性的患者可显著减少复发性流产的发生。Objectives]To investigate the relationship between anticardiolipin antibody(ACA),antibody to nuclear antigen(ANA),extractable nuclear antigen(ENA) and types of abortion and discuss its clinical significance.The venous plasma levels of ACA,ANA and ENA were estimated qualitatively in 68 cases of threatened abortion, 65 cases of recurrent spontaneous abortion(RSA), 22 cases of inevitable abortion and 26 cases of missed abortion.The distributions of ACA positive rate in different types of abortion showed significant disparity (P<0.05) ; whereas no significant difference was found among those of ANA and ENA in different types of abortion (P>0.05).[Conclusion]ACA is most closely related with RSA, then come to inevitable abortion, missed abortion and threatened abortion. Early diagnosis and treatment of ACA-positive patients may distinctly reduce the occurrence of RSA.

关 键 词：ACA ANA ENA 流产 表达 自发性流产 抗体 

分 类 号：R714.21[医药卫生—妇产科学]