金龙胶囊治疗HIV感染者20例初步报告  

A preliminary report on the effect of Jinlong capsule used in treating 20 cases of HIV infect patients

作　　者：吕维柏[1] 王健[1] 李建生 

机构地区：[1]中国中医研究院,北京100700 [2]北京鲜药研究中心,北京100039

出　　处：《中国艾滋病性病》2004年第1期18-19,35,共3页Chinese Journal of Aids & STD

摘　　要：目的　观察金龙胶囊对艾滋病病毒 (HIV)感染者的免疫增强作用。方法　 2 0例HIV感染者给以抗癌有效药物金龙胶囊 (鲜蛤蚧、鲜白花金钱蛇、鲜蝰蛇 ) ,分为小剂量组 (15例 ,每日 9个胶囊 )和大剂量组 (5例 ,每日12个胶囊 ) ,连续服用 3个月 ,治疗前后测定患者的病毒载量和CD4淋巴细胞计数。结果　治疗后 ,病毒载量除 3例减少 >0 5log,8例上升 >0 5log以外 ,其余均± <0 5log ,无明显变化 ;CD4细胞计数 :治疗后小剂量组 80 %CD4细胞计数明显升高 ,自 186 4 0± 110 92 /mm3 升为 30 0 73± 16 4 5 7/mm3 ,平均升高 114 33± 15 4 76 /mm3 ;大剂量组则自 2 5 7 17± 12 7 5 7/mm3 降为 2 4 2 37± 16 1 2 6 /mm3 ,平均下降 14 80± 12 0 4 0 /mm3 。结论　金龙胶囊可增强HIV感染者的免疫功能 。Objective To observe the immune-enhancing effect of Jinlong capsule in treating HIV-infected patients Methods Twenty HIV-infected patients were treated with an anti-cancer Chinese herbal medicine known as Jinlong capsule consisting of fresh gecko,fresh multibanded krait and fresh long-noded pit viper The patients were divided into small dosage group(9 caps/d,n=15)and large dosage group(12 caps/d,n=5),which orally took the capsule consecutively for 3 months Before and after the treatment,viral load and CD 4 cell count were determined Results After the treatment,except for 3 cases whose viral load was reduced by >0 5log, and 8 cases whose viral load was raised by >0 5log,all the other cases changed the load by less than 0 5log,which showed no significant difference;for CD 4 cell count,after treatment 80% of the patients in the small dosage group raised their count obviously,from 186 40±110 95/mm 3 to 300 73±164 57/mm 3,with a mean elevation of 114 33±154 76/mm 3,while the large dosage group lowered the count from 257 17±127 57/mm 3 to 242 37±161 26/mm 3,with a mean reduction of 14 80±120 40/mm 3 Conclusion Jinlong capsule could enhance the immune function of HIV-infected patients,but without significant HIV inhibiting effect

关 键 词：金龙胶囊 治疗 HIV感染者 艾滋病病毒 CD4细胞计数 免疫功能 

分 类 号：R512.91[医药卫生—内科学]