精子表面抗精子抗体与不育男性精液参数的临床分析  

Clinical Analysis on Checking Antisperm Antibody on the Surface of Semen and Male Immune Infertility

作　　者：楚雅玲[1] 岳林[2] 

机构地区：[1]河南科技大学第一附属医院检验科,洛阳471000 [2]河南省洛阳市中心医院生殖助孕中心

出　　处：《中国计划生育学杂志》2004年第3期162-164,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨精子表面抗精子抗体(AsAb)与精液主要参数的相关性。方法:使用安科公司MAR法(混合抗球蛋白反应试验)AsAb检测试剂盒进行精子表面AsAb检测,讨论观察组、对照组精液检测参数与AsAb的相关性。结果:不育组282例共检出AsAb阳性56例,阳性率达19.86％。抗体结合部位以头部为主,占46.4％。经相关分析,精液中AsAb的存在与精子密度、精子活率、精子活力(a级+b级)呈负相关(P<0.05)。结论:精子表面AsAb检测阳性时,可导致男性生育能力低下或不育。Objective: To discuss correlation between antisperm antibody on the surface of semen and main semen parameter. Methods: To examine AsAb on the surface of semen by MAR technique and reagent box produced by' ANKE Company and to discuss correlation between semen parameter in the observation group and in the control group and AsAb. Results: There were 56 cases with positive AsAb among 282 cases of male infertilities. Positive rate was 19. 86%. The main part combining with antibody was the head, which occupied 46. 4% . AsAb in semen had negative relationship with sperm concentration, motility (% )###a + b grade motile(P <0. 05). Conclusion: Antisperm antibody on the surface of semen causes the male low fertility or infertility.

关 键 词：精子表面抗精子抗体 不育男性 精液参数 临床分析 

分 类 号：R698.2[医药卫生—泌尿科学]