生长激素在短方案超排周期中的观察  

The Effect of Using Growth Hormone in Superovulation Cycles with Short Protocol

作　　者：李萍[1] 任建枝[1] 郑仁瑞[1] 韩冬梅[1] 黄扉[1] 

机构地区：[1]解放军第174医院生殖医学中心,福建厦门361003

出　　处：《临床军医杂志》2004年第1期43-44,共2页Clinical Journal of Medical Officers

摘　　要：目的　探讨在可疑卵巢储备力低下患者行体外受精 胚胎移植 (IVF ET)治疗时给予短方案并合用生长激素治疗的疗效。方法　对 2 0 0 0年 3月— 2 0 0 3年 3月由于有可疑卵巢储备力低下的原因接受IVF ET治疗而使用短方案控制超促排卵治疗 5 4人 ,其中加用生长激素 (GH)者 2 4人 ,设为研究组 ,未用GH者 3 0人 ,设为对照组。结果　两组在年龄、获卵数、受精率、卵裂率和妊娠率上无明显差异 (P >0 .0 5 ) ,卵巢反应不良上研究组明显低于对照组 (P <0 .0 2 5 )。结论　对可疑卵巢储备力低下者采取IVF ET治疗时可给予GnRHa短方案并合用生长激素 ,可减少卵巢反应不良和取消周期的发生 ,并可能提高妊娠率。Objective To study the effect of the GnRH-a short protocol and using growth hormone(GH) treatment in low ovarian reserve doubtfully. Methods There were 54 cases of the GnRH-a short protocol treatment in low ovarian reserve doubtfully for IVF-ET,which the studied group consisted of 24 cases of using GH and the control group consisted of 30 cases of no using GH.Results There were no statistically differences between the two groups in age and the rates of retrieved oocytes,fertilization,embryos cleaved and pregnancy(P>0.05).Poor ovarian responds was obviously lower in the studied group than in the control group(P<0.025).Conclusion Using GH in the GnRH-a short protocols low ovarian reserve doubtfully for IVF-ET can raise ovarian responds and diminish IVF-ET cycles cancelled.

关 键 词：生长激素 短方案 超排周期 体外受精 胚胎移植 生长激素 卵巢储备力低下 

分 类 号：R711.6[医药卫生—妇产科学]