内蒙草麻黄中生物碱的动态研究  

Studies of Seasonal Variation of Alkaloids Contained in Ephedra sinica Herba in Inner Mongolia

作　　者：程大敦[1] 郭平[1] 赵俊[1] 

机构地区：[1]南京药物研究所,210009

出　　处：《中国药科大学学报》1992年第2期82-87,共6页Journal of China Pharmaceutical University

基　　金：国家自然科学基金;卫生部基金

摘　　要：应用HPLC法研究了内蒙草麻黄主产区5种麻黄生物碱的动态变化。5种麻黄生物碱为:麻黄碱(E)、伪麻黄碱(PE)、去甲基麻黄碱(NE)、去甲基伪麻黄碱(NPE)和甲基麻黄碱(ME)。研究结果表明:内蒙东部的草麻黄生长期中E占优势,而在西部PE和E平行或PE高于E,总生物碱在7月中旬和9～10月达高峰。因此影响含量的主要因素是物侯期、降雨量和湿度。对地理位置、气象情况和退化现象等因素也进行了讨论。The seasonal variation of 5 active alkaloids, namely: Ephedrine E, Pseudoephedrine PE, Norephedrine NE, Norpseudoephedrine NPE and Methylephedrine ME contained in Ephedra sinica Herba were determined by HPLC. All of specimens were collected from 5 fixed observation areas in inner Mongolia where the plants were known to grow plentifully, and which send regular supplies to the factory at present time. In the east inner Mongolia E was predominant in all growing period, and in west, PE and E was nearly parallel or PE higher than that of E. The total alkaloid reaches their maximum in middle July and in September to October. The Authors suggested that the active factors affecting the content were ontogenetic stage, precipitation and relative humidity. The other active factors-geography, climate and degenerate phenomenon were discussed.

关 键 词：草麻黄 生物碱 

分 类 号：R284.1[医药卫生—中药学]