继发性甲状旁腺机能亢进的超声引导介入治疗与并发症  

Interventional Therapy for Secondary Hyperparathyroidism and its Complications

作　　者：李程[1] 杨琳[1] 刘亚绵[1] 张凌[2] 卞维静[2] 臧树良[1] 姚晓奇[1] 

机构地区：[1]中日友好医院超声诊断科,北京市100029 [2]中日友好医院血液净化中心,北京市100029

出　　处：《中国超声医学杂志》2004年第2期91-94,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的　探讨经皮向增生的甲状旁腺内注入无水酒精 (PEITP)治疗继发性甲状旁腺机能亢进 (secondary hyperparathyroidism,SHPI)的常见并发症、相关因素及预防措施。方法　分析比较 35例经治疗患者的治疗方法、疗效与并发症发生情况。结果　 35例患者经治疗其血清全段甲状旁腺素 (PTH)全部下降。缓解率 17.1% (6 / 35 ) ,显效率 5 1.4 % (18/ 35 ) ,满意率2 8.6 % (10 / 35 ) ,无效率 2 .9% (1/ 35 )。并发症 10例 ,其中疼痛 7例 ,出血 3例 ,声音嘶哑 2例。结论　PEITP是治疗继发性甲旁亢的有效方法 ,严格掌握治疗适应症 ,提高穿刺技术 ,临床治疗的密切配合是避免并发症的有效措施。Objective:To investigate the common complications,interrelated factors and the methods for preventing ultrasound guided percutaneous ethanol injection therapy of the parathyroid(PEITP)in chronic dialysis patients with secondary hyperparathyroidism.Methods:The therapeutic method,its effects,complications of thirty-five patients with PEITP were analysed and compared.Results:After therapy,PTH levels of 35 patients were all reduced.The remission rate was 17.1% (6/35),the remarkable effective rate was 51.4% (18/35),satisfaction rate was 28.6%(10/35),and failure rate was 2.9%(1/35).Ten patients had complications:seven patients had local pain,three patients had bleeding,two patients with hoarseness.Conclusions:PEITP is an effective and safe therapy.To strictly master the indications,to inprove the puncture technique and to cooperate clinically are effective means for preventing complications.

关 键 词：继发性甲状旁腺机能亢进 超声引导 介入治疗 并发症 无水酒精 慢性肾功能衰竭 

分 类 号：R582.1[医药卫生—内分泌]