阳离子聚合物纳米基因载体的研究进展  

Resenrch progress of the cationic polymer as the nanometric gene vector

作　　者：韦卫中[1] 吴华[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院核医学科，湖北武汉430030

出　　处：《医学研究生学报》2004年第4期355-357,共3页Journal of Medical Postgraduates

基　　金：国家自然科学基金资助项目 (批准号 :3 0 1710 62 )

摘　　要：由于阳离子聚合物等非病毒纳米基因导入载体安全、低毒、装载容量大、制备容易等优点已引起越来越多的关注 ,对提高其转导效率的研究也较多。该文作者对PLL和PEI等阳离子聚合物纳米基因载体的研究进展进行了综述。Cationic polymer, a kind of nonviral nanometric gene vector,have attracted more and more attention because they have many advantages in terms of low toxicity,lack of specific immune response,ease of large-scale production and big load.There are also many advance in how to increase the efficience of transduction.The anthor reviewed the advance of PLL and PEI as the nonviral nanometric gene vectors.

关 键 词：基因治疗 非病毒载体 阳离子聚合物 纳米 

分 类 号：Q782[生物学—分子生物学]