声学密度定量技术对周围动脉粥样硬化组织特征的研究  

Clinical study on the diagnosis of atherosclerosis in peripher al arteries by acoustic densitometry

作　　者：张园园[1] 张运[1] 张梅[1] 高月花[2] 李秀昌[1] 王燕[1] 王国亮 

机构地区：[1]山东大学齐鲁医院心内科,济南250012 [2]山西省人民医院内科 [3]单县人民医院超声科

出　　处：《中华超声影像学杂志》2003年第10期610-612,共3页Chinese Journal of Ultrasonography

基　　金：山东省卫生厅"九五"攻关项目( 971 1 );国家自然科学基金资助项目 ( 6 0 2 71 0 1 5)

摘　　要：目的　探讨声学密度定量技术 (AD)检测颈动脉及股动脉粥样硬化斑块组织特性的价值。方法　对 65例患者的颈动脉、股动脉管壁及粥样斑块进行组织定征 ,并采用管壁及斑块部位与外膜平均声学密度的比值 (AIIr)作为定量指标。结果　动脉内膜AIIr与动脉僵硬度 β呈高度正相关关系 (r=0 .75,P <0 .0 0 1) ,股动脉内膜AIIr显著高于颈动脉 ,60岁以上患者动脉内膜AIIr大于 60岁以下者。斑块不同组织学构成的AIIr分别为 :脂质型斑块 62 .2 5%± 4.56% ,纤维型斑块 79.92 %± 8.87% ,钙化型斑块 110 .2 6%± 9.2 6%。Objective To study histological characteristics of atherosclerotic plaque in carotid and femoral arteries with acoustic densitometry (AD) technique.Methods The carotid and femoral arteries were examined in 65 patients by ultrasound AD technique with average image intensity ratio (AIIr) as the statistical index.Results The AIIr values of intima correlated well with the arterial stiffness β(r= 0.75 ,P< 0.001 ),and the values in femoral arteries were higher than those in carotid.Meanwhile,the AIIr values of intima in patients older than 60 years old were higher than younger ones.The AIIr values of histologically different plaques were: fatty 62.25 %± 4.56 %,fibrous 79.92 %± 8.87 % and calcify plaques 110.26 %± 9.26 %.Conclusions AD can distinguish different histological plaques and evaluate the elasticity of the artery.

关 键 词：声学密度定量 颈动脉粥样硬化 股动脉粥样硬化 斑块特征 超声心动描记术 诊断 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]