子宫内膜下螺旋动脉血流评估子宫内膜接受性的初步探讨  

Preliminary study on assessment of endometrium receptivity with parameters of spiral artery blood flow

作　　者：贡雪灏[1] 张青萍[1] 朱桂金[2] 乐桂蓉[1] 肖先桃[1] 黎春雷[1] 程文[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声影像科,武汉430030 [2]华中科技大学同济医学院附属同济医院医学生殖中心,武汉430030

出　　处：《中华超声影像学杂志》2003年第9期538-540,共3页Chinese Journal of Ultrasonography

摘　　要：目的　应用经阴道彩色多普勒超声初步探讨子宫内膜下螺旋动脉血流作为胚胎移植前评价内膜接受性指标的临床价值。方法　对 94例辅助生殖技术治疗结果不同 (妊娠或未孕 )的不孕妇女内膜下螺旋动脉的血流进行回顾性比较分析。结果　胚胎移植前 ,妊娠者螺旋动脉血流阻力明显低于未孕者 ,其阻力指数 (RI)、收缩期和舒张期血流速度比值 (S/D )的差异具有非常显著性意义 (分别为 0 .62± 0 .0 4对 0 .68± 0 .0 4,P <0 .0 0 1;2 .66± 0 .3 3对 3 .19± 0 .3 9,P <0 .0 1) ;搏动指数 (PI)在两种妊娠状况下的差异具有显著性意义 (1.15±0 .17对 1.3 4± 0 .2 2 ,P <0 .0 5 )。当RI >0 .72、PI >1.6、S/D >3 .6时 ,多为无妊娠者。结论　螺旋动脉血流动力学参数能够作为评估内膜接受性的有效指标 ,供胚胎移植前参考。Objective To evaluate whether the parameters of spiral artery blood flow,as measured by transvaginal color Doppler,may be used to assess endometrium receptivity prior to embryo transfer (ET).Methods A retrospective study of 94 infertile women who had undergone the assisted reproductive technology(ART) treatments with different outcomes(pregnant or non-pregnant).Blood flow of endometrium was evaluated.Results The resistance index(RI),systolic/diastolic ratio (S/D) and pulsatility index(PI) were significantly lower in those who achieved pregnancy as compared with those who did not(respectively 0.62 ± 0.04 vs 0.68 ± 0.04 , P < 0.001 ; 2.66 ± 0.33 vs 3.19 ± 0.39 , P < 0.01 and 1.15 ± 0.17 vs 1.34 ± 0.22 , P < 0.05 ).Furthermore,when RI> 0.72 ,PI> 1.6 ,S/D> 3.6 ,no pregnancy occurred.Conclusions The parameters of spiral artery blood flow could be used as a marker for assessing endometrial receptivity before the time of embryo transfer.

关 键 词：螺旋动脉血流 子宫内膜接受性 不孕 胚胎移植 彩色多普勒超声检查 

分 类 号：R725.4[医药卫生—儿科]