还少丹胶囊抗衰老及治疗肾阳虚临床观察  

Study of Effect on Anti-Aging and Treating Yang(阳)-Deficiency of Kidney with Huanshao Dan(还少丹)Capsules——A Clinical Report of 309 Cases

作　　者：杜辛[1] 杨仁旭[1] 陈小沁[1] 张仲莲[1] 李玉芳[1] 谢淑仪[1] 吴永刚[1] 徐永秀[1] 申仲华[2] 高华宇[2] 章凯[2] 许永春 谭力 陆灿红 

机构地区：[1]成都中医学院附属医院,成都610072 [2]成都市第二人民医院 [3]四川省草堂干部疗养院

出　　处：《中国中西医结合杂志》1992年第1期20-22,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：采用中药古成方还少丹胶囊,对309例中老年肾虚患者,以不同剂量进行为期1.5～3个月治疗,并与还少丹水泛丸及安慰剂以单盲或双盲法进行对比观察。结果:还少丹胶囊大、小剂量组(Ⅰ、Ⅱ)组,还少丹水泛丸大、小剂量组(Ⅲ、Ⅳ组)及胶囊小剂量短疗程组(Ⅴ组)治疗前后症状记分比较,差异均有显著性意义(P<0.001,<0.01),而安慰剂组治疗前后差异无显著性意义。Ⅰ～Ⅳ组的近视力、握力、心理衰老、瞬时记忆记分治疗后均有明显改善(P<0.05):血清过氧化脂质、肾上腺皮质激素、超氧化物歧化酶、细胞免疫功能等.治疗后均有改善.与安慰剂组比较P<0.05,胶囊组与水泛丸组比较差异不显著(P>0.05),说明两种剂型均有抗衰老及补肾作用。In this study, with various dosages of Huanshao Dan capsules, an old Chinese medicine formula, the authors treated the patients with Yang-deficiency of Kidney for 1.5～3 months and compared the effects of Huanshao Dan with those of watered pills and placebo. The analyses of Ridit's showed not only the scores of symptoms of the great-dose Huanshao Dan group (group 2), the great-dose watered pill group (group 3), the small-dose watered pill group (group 4) and but even the short-trating course group (group 5) were remarkably improved after treatment (P<0.001,.P<0.01); but the group 6 have not any difference after treatment. However, the functions of liver and kidney, the level of cholesterol, the concentration of blood sugar, blood pressure and heart rate remained the same after treatment. The scores of the ability of prompt memory as well as serum lipid peroxide, serum adrenocortical hormone, cellular immunol function, index of glycoprotein and T_3, T_4 had similar changes. Our data suggested that both Huanshao Dan and watered pills werebeneficial for anti-aging process and there was no noticeable difference between the two drugs.

关 键 词：还少丹 抗衰老 肾阳虚 

分 类 号：R285.6[医药卫生—中药学]