双黄连气雾剂稳定性的研究  

Studies on the Stability of Shuang Huanglian Aerosol

作　　者：徐凯建[1] 张慧君[1] 吴琳华[1] 陆义诚[1] 孙考祥[1] 姚志国 

机构地区：[1]哈尔滨医科大学临床药学药物研究所,150086

出　　处：《中国中药杂志》1992年第3期157-159,共3页China Journal of Chinese Materia Medica

摘　　要：采用高压液相色谱法测定了双黄连气雾剂中绿原酸与黄芩甙的含量,应用恒温加速实验法探讨了双黄连气雾剂的化学动力学过程,预测其稳定性,实验结果与留样观察法相近,同时对双黄连在降解过程中pH的变化进行了考察。The contents of chlorogenic acid and baicalin in Shuang Huanglian Aerosol were determined by HPLC. The process of chemical kinetics of the aerosol was studied by constant temperature acceleration tests, and the stability of the drug predicted. The results appeared close to those from the stored sample method. pH changes during degradation of the drug were also observed.

关 键 词：双黄连气雾剂 绿原酸 稳定性 

分 类 号：R285.5[医药卫生—中药学]