氟哌啶与曲马多联合应用于普胸外科术后镇痛的观察  

Clinical observation on the postoperative analgesic effect of droperidol combined with tramadol in general thoracic surgery

作　　者：李梅岭 耿昕 於太斌 赵长虹 赵丽 张金铎 谢荣景 李保庆[2] 

机构地区：[1]河北省沧州市人民医院胸外科,061000 [2]河北医科大学第四医院胸外科

出　　处：《河北医药》2004年第3期239-240,共2页Hebei Medical Journal

摘　　要：目的　应用微量泵持续静脉输注曲马多及氟哌啶 (CTD)进行普胸外科术后镇痛的观察。方法　 114例患者随机分为两组 ,试验组接受CTD镇痛 ,对照组应用间断肌肉注射杜冷丁 (IMD)镇痛。结果　两组不同镇痛方法后 2h及术后 48h内镇痛效果比较 ,差异非常显著 (P <0 .0 1) ,两组患者术后48h内睡眠时间分别为 ( 16.3 6± 1.8)和 ( 7.62± 1.3 1)h(P <0 .0 1)。术后呕吐例数分别为 1例和 14例(P <0 .0 1)。两组呼吸功能及心功能的比较差异无显著性 (P >0 .0 1)。结论　微量泵持续静脉输注曲马多加氟哌啶镇痛效果优于常规间断肌肉注射杜冷丁法。Objective To evaluate the postoperative analgesic effect of continuous infusion of tramadol and droperidol (CTD) by micropump in general thoracic surgery.Methods 114 patients were randomly divided into two groups.58 patients in trial group were treated by CTD;56 patients in control group were treated by intermittent intramuscular injection of dolantin (IMD),and the analgesic effects in both groups were observed.Results There was a significant difference in analgesic effects between the two groups (P<0.01).The sleeping time was 16.36±1.80 in trial group and 7.62±1.31 in control group within 48 hours after operation respectively (P<0.01).The cases of vomiting were 1 and 14 respectively (P<0.01).There was no significant difference in the respiratory function and cardiac function between two groups (P<0.01).Conclusion The analgesic effect of continuous infusion of tramadol and droperidol by micropump is superior to that of intermittent intramuscular injection of dolantin.

关 键 词：氟哌啶 曲马多 联合用药 胸外科 术后镇痛 呼吸功能 心功能 微量泵 

分 类 号：R971.2[医药卫生—药品] R655[医药卫生—药学]