超声检查及血清CA_(125)测定诊断子宫腺肌病的评价  

Clinical Evaluation of Ultrasonography and Serum CA_(125) in Diagnosis of Adenomyosis

作　　者：康佳丽[1] 夏薇[1] 何谦谊[1] 聂妙玲[1] 卢丽娜[1] 杨新[1] 

机构地区：[1]广东省广州市第一人民医院,广东广州510180

出　　处：《实用妇产科杂志》2004年第2期96-97,共2页Journal of Practical Obstetrics and Gynecology

基　　金：广东省卫生厅科技项目资助 (编号 :A2 0 0 2 565)

摘　　要：目的 :探讨超声检查及血清癌抗原 12 5 (CA12 5)测定对子宫腺肌病的诊断价值。方法 :通过对 12 0例疑为子宫腺肌病或子宫肌瘤患者 ,行术前腹部B超和血清CA12 5测定 ;术后切下组织送病理学检查确诊并与之对照。结果 :经术后病理学证实 :子宫腺肌病组术前血清CA12 5检测敏感度 73.8% ,特异度 73.5 % ;B超诊断该病的敏感度 5 5 .4 % ,特异度 6 4 .8% ;以两种方法联合检测均阳性为诊断标准 ,则敏感度 5 2 .5 % ,特异度 94 .1%。结论 :测定血清CA12 5水平 ,对子宫腺肌病是较好的辅助诊断指标 ;B超检查对该病有一定诊断价值 ;两者联合检测能提高诊断的正确性 ,且方法简便、快捷、无创伤 。Objective: To investigate the diagnostic value of ultrasonography and serum CA 125 in adenomyosis. Methods: 120 cases of adenomyosis and myoma of uterus were analysed. All cases were carried out the ultrasonography of type B and detected the serum CA 125 before operation, and then compared with the postoperative pathological examination which could make accurate diagnosis. Results: The positive rate and specificity of serum CA 125 for diagnosis of adenomyosis were 73.8% and 73.5%. The sensitivity and specificity of ultrasonography of type B for diagnosis of adenomyosis were 55.4% and 64.8%. If combining these two methods as diagnostic criteria, the sensitivity and specificity were 52.5% and 94.1%. Conclusions: The determination of serum CA 125 is helpful for the auxiliary diagnosis of adenomyosis. Ultrasonography is rather valuable for the diagnosis of adenomyosis. The diagnostic accuracy may be enhanced after combining them that provide quick, convenient, noninvasive, and practical diagnostic method.

关 键 词：超声检查 血清学检查 CA125 子宫腺肌病 诊断标准 

分 类 号：R711.74[医药卫生—妇产科学] R445.1[医药卫生—临床医学]