冠状动脉腔内成形术加支架置入术预防冠状动脉再狭窄的临床研究  

Clinical study of intracoronary stenting on preventing coronary restenosis after percuteneous transluminal coronary angioplasty

作　　者：高文献 付存玉 张志刚 杨树国 袁敏 

机构地区：[1]沂水中心医院,山东临沂276400

出　　处：《山东医药》2004年第11期1-2,共2页Shandong Medical Journal

摘　　要：目的 探讨冠状动脉支架预防经皮冠状动脉(下简称冠脉)腔内成形术(PTCA)后冠脉再狭窄的效果及活动平板试验诊断冠脉再狭窄的价值。方法 将60例PTCA成功者随机分为联合组和PTCA组,联合组在PTCA基础上置入支架,PTCA组单纯行PTCA。两组均于术后1周及6个月分别行次极量活动平板试验;术后6个月重复冠脉造影,观察两组冠脉再狭窄率。结果 联合组术后即刻狭窄率低于PTCA组(P<0.01),术后6个月仍有明显差异(P<0.001),术后6个月两组13例冠脉再狭窄者活动平板试验阳性11例,占84.62％。结论冠脉支架置人具有预防PTCA术后冠脉再狭窄的作用,活动平板试验结合心绞痛复发症状可检出冠脉再狭窄的高危患者。Objective To investigate the effect of intracoronary stenting on preventing coronary restenosis after percuteneous transluminal coronary angioplasty(PTCA) and the diagnostic value of treadmill exercise test on restenosis. Methods 60 cases with coronary disease were divided randomly into combined group and PTCA group. Stents were implanted after PTCA in patients of the combined group. Coronary angiographies were performed 6 months after PTCA,meanwhile treadmill exercise tests were assessed 1 week and 6 months after the procedures. Results The immediate residual stenosises in combined group were lower than those of PTCA group (P<0.01), and the same significance could be seen 6 months after the procedures (P<0.001). There were 11 cases with positive of treadmill exercise test in 13 cases of restenosis 6 months after PTCA. Conclusion Intracoronary stenting can reduce the restenosis rate after PTCA, and treadmill exercise test combined with anginapectoris is sensitive in the diagnosis of restenosis.

关 键 词：冠状动脉腔内成形术 支架置人术 预防 冠状动脉再狭窄 临床研究 

分 类 号：R654.3[医药卫生—外科学]