宫环Ⅱ号胶囊对宫环出血患者月经血中NO水平及免疫因素影响的研究  

Effect of Gonghuan Ⅱ Capsule on Level of NO and Immune Factor in Patients' Bleeding after IUD Placement

作　　者：张烨 尤昭玲[2] 文乐兮[2] 

机构地区：[1]深圳市福田区中医院,广东深圳518034 [2]湖南中医学院,湖南长沙430071

出　　处：《中国中医基础医学杂志》2004年第1期67-69,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：湖南省科学技术厅科技计划重点项目 ( 0 1SSY10 0 0 2 4);湖南省科学技术厅科技计划社会发展领域一般项目 ( 0 3SSY40 40 )资助

摘　　要：目的 :探讨宫环出血病病理生理机制。方法 :(1) 6 0例气虚血瘀型宫环出血患者完全随机分为GHⅡ治疗组和吲哚美辛对照组 ,7d为 1个疗程。 (2 )采用放射免疫等方法观察宫环出血患者治疗前后月经血中NO、NOS、免疫五项的改变。结果 :GHⅡ降低宫环出血患者月经血中NO水平 ;降低宫环出血患者月经血中C3、C4、IgG、IgA水平。结论 :GHⅡ的作用机制在于 :调整局部血管舒缩因子 (如NO)水平 ,使血管舒缩状态趋于正常 ;调整局部免疫状态 (如降低C3及IgG、IgA、IgM水平 )。Objective: To Discuss Pathophysiological Mechanism of Bleeding after IUD Placement.Methods: 1.60 Bleeding after IUD Placement Patients Were Randomly Divided into Two Group Including GHⅡ Treated group(n=30)and western Medicine Control Group(n=30)。GHⅡ were Orally Taken at Dose of 16g/d(8g,Bid)in GHⅡ Treated Group,1 course Including One Week.Indomethacin Were Orally Taken at Dose of 0.5/d(0.25,Bid)in Western Medicine Control Group and The Treatment Course Was Same as GHⅡ Treated Group.Lists of Clinical Observation Were Full in After One Course.Radio-immunity were Adopted to Observe Alteration of NO、C 3、C 4、IgG、IgA、IgM in Menorrhea Were Observed.Results: Level of NO in Patients' Menorrhea Were Decreased.Level of C 3、C 4、IgG、IgA in Blood of Menorrhea Were Decreased.Conclusion:The Mechanism of GHⅡ MayBe Conclude:Level of NO、C 3、C 4、IgG、IgA in Menorrhea or Endometrium Were Ameliorated after Treated by GHⅡ.

关 键 词：宫环Ⅱ号胶囊 宫环出血 月经血 NO 免疫学 一氧化氮 避孕方法 

分 类 号：R271.11[医药卫生—中医妇科学] R286[医药卫生—中医学]