移动电话微波辐射对人皮肤角朊细胞损伤的研究  

The Effect of Mobile Phone Microwave Radiation on Cultured Keratinocytes

作　　者：张淑芝[1] 姚耿东[1] 沈鹏[1] 

机构地区：[1]浙江大学医学院公共卫生系,浙江杭州310031

出　　处：《浙江预防医学》2004年第5期1-2,8,共3页Zhejiang Journal of Preventive Medicine

摘　　要：目的　探讨移动电话微波辐射对体外培养人皮肤角朊细胞的影响。方法　体外培养的人皮肤角朊细胞 (HaCaT细胞 )暴露于或假暴露于频率为 1 8GHz、SAR为 1W /Kg、 2W/Kg、 3W/Kg的模拟移动电话微波辐射 4小时后 ,检测乳酸脱氢酶 (LDH)活力及细胞死亡率。结果　在SAR 3W/Kg组可引起细胞死亡率的增高 ,为 13 4± 0 1,与对照组 12 0± 0 1相比 ,有显著性差异 (P <0 0 5 ) ;在SAR 2W /Kg和SAR 3W/Kg组 ,培养液中LDH活力值 (U/L)增高 ,分别为 13 42 7± 2 2 6 4和 14 14 1± 13 4 7,与对照组LDH活力值 10 17 6±2 0 4 5U/L和 985 9± 2 74 9U/L相比 ,有显著性差异 (P <0 0 5 )。结论　移动电话微波辐射对体外培养人皮肤角朊细胞有损伤作用。Objective To investigate the effect of mobile phone microwave radiation on cultured keratinocytes. Methods The keratinocytes were exposed or non-exposed to microwave radiation for 4 hours with frequency of 1 8GHz, the average specific absorption rate (SAR) at three levels of 1W/Kg, 2W/Kg and 3W/Kg, respectively.The lactate dehydrogenases (LDH) and cell death rate were detected. Results The level of LDH and cell death rate in the exposure groups with SAR of 3W/Kg were significantly higher than those in the control groups. The level of LDH was also found significantly increased in the exposure groups with SAR of 2W/Kg. However, no significant difference was found between the exposed group SAR of 1W/Kg and controls. Conclusions The microwave radiation of mobile phone can cause some damage on keratinocytes.

关 键 词：移动电话 微波辐射 皮肤角朊细胞 细胞损伤 乳酸脱氢酶 

分 类 号：R122.4[医药卫生—环境卫生学]