MnDPDP的MR增强扫描在肝脏病变中的应用  

MnDPDP enhanced magnetic resonance imaging of focal liver lesion

作　　者：刘燕丽[1] 宦怡[1] 葛雅丽[1] 魏光全[1] 常英娟[1] 张劲松[1] 赵海涛[1] 

机构地区：[1]第四军医大学西京医院放射科,陕西西安710033

出　　处：《第四军医大学学报》2004年第4期351-354,共4页Journal of the Fourth Military Medical University

摘　　要：目的 :评价与探讨MnDPDP增强MR扫描在肝脏病变中的影像表现及诊断价值 .方法 :收集肝脏病变患者 1 3人 ,其中 1 1例经手术或病理活检证实 ,2例经影像为主的综合检查证实 ,均行T1 WI及T2 WI扫描 (T1 FFE ,T1 TFE ,T2 TSE序列 ) ,注入 0 .5mL/kgMnDPDP后 2 0min及 2 4h分别行T1 WI扫描 .结果 :6例肝细胞型肝癌于MnDPDP增强后表现为不同程度的强化 ,1例FNH及 1例肝腺瘤无明显强化或轻度均匀一致强化 ,2例肝血管瘤及 3例肝转移瘤无强化 ,但 3例转移瘤2 4h延迟后可见周围肝组织内环形强化 ,并于 2 4h后发现更多小病灶 .结论 :MnDPDP作为一种新型的MR对比剂 。AIM: To study the MnDPDP enhanced magnetic resonance imagings and to assess their diagnostic value in MR examination. METHODS: Thirteen patients with hepatic lesions were included in this study, 11 cases of which had been confirmed by either operation or biopsy. T 1WI (T 1 FFE, T 1 TFE ) and T 2WI (T 2 TSE) were performed prior to the administration of contrast agent. T1 weighted images were then obtained at 20 min and 24 h following intravenous infusion of 0.5 mL/kg MnDPDP. RESULTS: Six cases of hepetocellular carcinoma showed detectable enhancement with MnDPDP, varying patterns of enhancement were obtained. In 1 case of focal nodular hyperplasia (FNH) and 1 case of hepatocellular adenoma, lesions appeared iso intense or hyper intense compared with normal liver in early phase imaging. In 2 cases of liver haemangioma and 3 cases of liver metastases, lesions did not enhance with MnDPDP. CONCLUSION: As a new contrast agent used in magnetic resonance imaging of the liver, MnDPDP is of some value in detecting hepatic lesions and in differential diagnosis.

关 键 词：锰福地匹三钠 磁共振成像 肝/病理学 

分 类 号：R445.2[医药卫生—影像医学与核医学]