109人发角蛋白人工腱-特制生物膜复合体的实验研究  

An experimental study of the implantation of an epitendineum-109 human hair artificial tendon complex in rabbits

作　　者：谢琦[1] 曹启迪[2] 

机构地区：[1]中国人民解放军第303医院骨科,广西南宁530021 [2]第一军医大学南方医院骨科,广东广州510515

出　　处：《第一军医大学学报》2003年第6期584-586,共3页Journal of First Military Medical University

基　　金：国家自然科学基金(39070813)~~

摘　　要：目的研究109人发角蛋白(109HH)人工腱-特制生物膜复合体植入体内的可行性。方法制备可吸收性109HH人工腱和特制的腱膜,并将人工腱-腱膜复合体或单纯人工腱植入兔体内,于不同时间点观察植入物的变化。结果109HH人工腱-特制生物膜复合体被逐渐吸收,并逐渐被正常肌腱替代,与周围组织无粘连,未见瘢痕组织形成。结论该复合体植入体内是可行性的。Objective To study the feasibility of in vivo implantation of an epitendineum-109 human hair (109HH) artificial tendon composite. Methods An absorbable epitendineum-109HH artificial tendon complex was implanted into rabbits to observe its changes at different time points. In control groups, 109HH artificial tendons or the artificial tendon-Dacron complex were implanted instead. Results and Conclusion The epitendieum-109HH artificial tendon complex was gradually but finally completely absorbed by the surrounding tissues to be replaced by normal tendon without conglutination or scar formation, approving the feasibility of the implantation of epitendineum-109 human hair artificial tendon complex in vivo.

关 键 词：人发角蛋白 人工腱 生物膜 复合体 实验研究 腱膜 人工器官 

分 类 号：R318.17[医药卫生—生物医学工程]