发育阶段人脑视觉系统微血管密度的增龄变化  

Aging variance of microvascular density in developing visual system of human brain

作　　者：吕华[1] 郭旭方[1] 赵全明[1] 

机构地区：[1]山西医科大学解剖学教研室,太原030001

出　　处：《解剖学杂志》2004年第1期43-46,共4页Chinese Journal of Anatomy

基　　金：山西省自然科学基金 (9710 5 3)

摘　　要：目的 :探讨人脑视觉系统微血管密度增龄变化与视觉发育的关系及其规律。方法 :采用碱性磷酸酶染色法 ,对 7例新生儿和婴幼儿脑视觉系统微血管密度进行定量分析。结果 :微血管密度在不同年龄、不同区域均存在着差异。同一区域内的微血管密度随年龄增加而增大 ,不同区域内微血管密度大小的排序新生儿组和婴儿组为LGN>1 7区 >1 8区 >1 9区 >SC >Pul>3 9区 >;幼儿组为LGN >1 7区 >1 8区 >1 9区 >3 9区 >SC >Pul。随年龄增加大脑皮质微血管的层次及形态也发生变化 ,层次由新生儿的 3层发展为婴幼儿的 4层 ,形态由简而繁 ,越来越复杂。结论 :人脑视觉系统微血管密度的增龄变化与视觉发育存在着相关性和同步性 ,同样遵循由尾至头的发育规律。Objective:To discuss the relationship aging variance of the microvascular density and development in visual system of human brain. Methods:The microvascular densities were observed and analyzed in alkaline phosphatase-stained sections of human visual system from 7 neonates, infants and child brains. Results:The microvascular densities increased in the same areas with the increase of age. In different areas, the microvascular densities was in the order of:LGN>17>18>19>SC>Pul>39 in the neonates and infants, and was LGN>17>18>19>39>SC>Pul in the children. There were 3 layers of the microvascular network within cerebral cortex of the neonates and 4 layers of the infants and the children. Conclusion:The aging variance of the microvascular density in visual system of human brain is closely related to the visual development.

关 键 词：微血管密度 视觉系统 碱性磷酸酶染色法 脑血管 年龄 形态学 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学]