分娩前后血清生长激素变化的观察  

Observations on the Perinatal Changes of Maternal Serum Growth Hormone Levels

作　　者：法逸华[1] 苏成海[1] 

机构地区：[1]苏州大学附属第一医院核医学科,硕士研究生215006

出　　处：《放射免疫学杂志》2004年第2期89-90,共2页Journal of Radioimmanology

摘　　要：目的 :了解女性血清生长激素 (GH)在妊娠期及分娩前后的变化。方法 :采用放射免疫分析 (RIA)检测 76例正常非孕期妇女、6例妊娠晚期妇女、32例临产期妇女和 2 0例产褥期妇女的血清生长激素 (GH)。结果 :妊娠晚期和临产组血清GH含量明显高于正常组和产褥组 ,差异有显著性 (p <0 0 1 ) ;妊娠晚期组与临产组无明显差异 (p >0 0 5 )产褥组与正常组也无明显差异 (p >0 0 5 )。 结论 :GH在妊娠后期和临产期明显升高 ,反映了母体的正常功能 ,为胎儿的正常发育所必需。分娩后迅速恢复正常 。Objective To investigate the changes of maternal serum GH levels during late gestation and soon (24 hours) after delivery. Methods Serum GH levels were measured with RIA in 6 women during late pregnancy, 32 pre-delivery women, 20 women soon after delivery and 76 controls (normal non-pregnant women). Results Serum GH levels in the late pregnant (20 1±1 87μg/L) and pre-delivery (21 07±7 77μg/L) women were significantly higher those in women soon after delivery (2 76±0 88μg/L) and controls (2 73±2 15μg/L) ( p <0 01). There was no significant difference between the levels in late pregnant and pre-delivery women, nor between those in the controls and women soon after delivery. Conclusion Elevation of maternal serum GH levels during pregnancy reflects the normal maternal adaptation to meet the demand for fetal growth. However, the origin of increase is mainly from the placenta (placental GH or HGH-V) rather than from the pituitary (HGH-N); hence the rapid decline soon after delivery.

关 键 词：分娩 血清 生长激素 GH 妊娠期 放射免疫 

分 类 号：R714[医药卫生—妇产科学]