QCT对骨质疏松的早期诊断及疗效观察研究  

The Study of the Earlier Period Diagnostic Criterion and Curative Effects of Osteoporosis by QCT

作　　者：朱江[1] 陆跃武[1] 高华康[1] 宋家明[1] 杨耀祖[1] 

机构地区：[1]安徽省淮北市人民医院,安徽淮北235000

出　　处：《潍坊医学院学报》2004年第1期22-24,共3页Acta Academiae Medicinae Weifang

基　　金：安徽省淮北市科技局资助课题 (课题编号 :0 2 1 0 37)

摘　　要：目的　研究骨质疏松的早期诊断的QCT标准及对骨质疏松治疗前后的效果观察。方法　使用西门子SOMATOMEMOTION型定量CT ,利用其骨质疏松测定软件 ,测定正常及骨质疏松的病人的骨密度 ,并测定其碱性磷酸酶、血生化、血钙等骨代谢指标 ;结合其他医院的研究结果 ,探索骨质疏松的早期诊断方法 ;对骨质疏松的病人正规治疗后 3个月 ,利用QCT观察骨密度变化。结果　由QCT查出的骨密度与DEXA查出的骨密度峰值有所不同 ,其高峰在 2 0岁左右 ,用QCT观察骨密度变化 ,可在 3个月内观察到骨密度的明显变化。结论　QCT可在较短的时间内观察到骨密度的变化 ,QCT监测疗效的优点是明显的 ;骨质疏松的早期诊断可由两点观察骨密度的变化来实现。Objective To study the earlier period diagnostic criterion of osteoporosis by QCT(quantitative computed tomography) and observe osteoporopsis curative effect.Methods Use SIEMENS SOMATOM quantitative CT and its BMD measure software to scan of the the second,third and fourth lumbar vertebral for BMD in healthy subjects and moreover mensurat AKP,blood calcium and the other bone metabolize index;And link the other hospital's result to study the earlier period diagnostic criterion of osteoporosis by QCT;Regularity cure the osteoporosis subjects for three months,and then observe their BMD's change by QCT.Results The peak values of BMD by QCT mensurating are different from that mensurated by DEXA.Their max values are about 20 years old.It can measurate in three months the obvious variety of the BMD after three months of regular treatment in osteoporosis subjects.Conclusion The QCT can observe in shorter time the variety of the BMD.The advantages of the curative effect of the QCT monitors is obvious;The earlier period diagnosis of osteoporopsis can be realized by observing the BMD's change from two points.

关 键 词：骨质疏松症 定量CT 骨密度 诊断 

分 类 号：R814.42[医药卫生—影像医学与核医学] R336[医药卫生—放射医学]