MRI在Chiari畸形颅脑体积测量中的应用价值  

Value of MRI in cerebral volume measurement in patients with Chiari malformation

作　　者：韩霞[1] 王春柳[1] 

机构地区：[1]尚志市人民医院磁共振室,黑龙江150600

出　　处：《放射学实践》2004年第2期95-97,共3页Radiologic Practice

摘　　要：目的 :研究MRI在Chiari畸形颅脑体积测量中的临床应用价值与意义 ,为临床开展定量后颅窝扩大成形术治疗Chiari畸形提供依据。方法 :采用象素体积测量法 ,对正常人、Chiari畸形患者分别进行全脑、后颅窝体积测量 ,计算幕下 /幕上体积之比 ,并进行统计学分析。结果 :对照组 3 5例正常人全脑体积平均值为 15 5 4.3 1cm3 ,后颅窝体积平均值为2 0 5 .43cm3 ;幕下 /幕上体积之比平均值为 0 .15 2。Chiari畸形组 2 2例患者全脑体积平均值为 14 5 7.85cm3 ,后颅窝体积平均值为 172 .84cm3 ,幕下 /幕上体积之比平均值为 0 .13 4。病人组与正常对照组的全脑体积、后颅窝体积、幕下 /幕上之比的P值分别为 0 .0 612、0 .0 0 173和 0 .0 0 10 8,差异具有显著性意义。后颅窝扩大成形术后 ,后颅窝体积扩大平均值为 16.7cm3 。结论 :采用MRI对Chiari畸形患者进行颅脑体积、后颅窝体积测量 ,数据准确可靠 ,能为临床开展定量后颅窝扩大成形术治疗Chiari畸形提供准确数据 。Objective:To study the value and clinical significance of MRI for cerebral volume measurement in patients with Chiari malformation,and to provide some basic understanding about the posterior fossa cranioplasty (EPFC).Methods:Pixel volume measurement (PVM) had been taken to measure cerebral volume and posterior fossa volume of normal subjects and patients with Chiari malformation,and to count the ratio of them (infra /supra tentorial volume).Results:The average cerebaral volume in 35 normal subjects was 1554.31cm 3,the average posterior fossa volume was 205.43cm 3,the infra /supra tentorial ratio was 0.152.In 22 cases of Chiari malformation,the average cerebral volume was 1457.85cm 3,the average posterior fossa volume was 172.84cm 3,and the ratio was 0.134.The difference was statistically significant (P 0.01). After EPFC,the volume of posterior fossa had increased 16.7cm 3.Conclusion:MRI has great value for cerebral volume measurement in patients with Chiari malformation. It provides better understanding for evaluation of therapeutic effects after posterior fossa cranioplasty.

关 键 词：CHIARI畸形 颅脑体积 定量后颅窝扩大成形术 磁共振成像 脊髓空洞症 并发症 

分 类 号：R445.2[医药卫生—影像医学与核医学]