应用镁离子治疗急性重型颅脑损伤的临床观察  

Clinical study of Mg^(2+) in treating acute severe brain injury

作　　者：顿志平[1] 王洪亮[1] 冯承泉[1] 谢永胜[1] 尚景瑞[1] 赵奎[1] 

机构地区：[1]武警山东总队医院神经外科,济南250014

出　　处：《武警医学院学报》2003年第4期261-262,共2页Acta Academiae Medicinae CPAPF

摘　　要：目的 :研究Mg2 + 在急性重型颅脑损伤中的治疗作用。方法 :对符合标准的 10 3例病人随机分为对照组 (常规疗法 )和实验组 (常规治疗加上MgSO4 ) ,观察下列临床指标 ,包括病人一般情况、心血管系统、颅内压、脑水肿、死亡率、GCS和GOS。结果 :经统计分析 ,Mg2 + 治疗组心血管系统表现异常率下降 ,脑水肿减轻 ,颅内压下降 ,死亡率降低 ,预后改善。结论 :Mg2 + 在急性重型颅脑损伤中发挥重要治疗作用 ,应该提倡使用。Objective:To approach the rold of Mg 2+ in treating acute severe brain injury.Methods:103 cases were divided into two groups by random,the control group(n=51) was provided routine therapy and Mg 2+ was added to the trail group(n=52).Then,observed the clinical datas,including the general information,arrhythmia or cardiac ischemia,vasopressure,brain edema,intracranial pressure,mortality,GCS,and GOS.Results:By statistical analysis,the trial group′s rate of arrhythmia or cardiac ischemia and abnormal vasopressure was lowered,mortality was also decreased,and outcome was improved.Conclusion:Mg 2+ played a vital role in treating the acute severe brain injury for the patient′s better prognosis.

关 键 词：镁离子 急性重型颅脑损伤 治疗 

分 类 号：R651.15[医药卫生—外科学]