抗生素调节竞争菌群失调的数学模型分析  

Mathematical model of regulating competitive dysbacteriosis with antibiotics

作　　者：樊爱军[1] 王开发[1] 邓国宏[2] 刘俊康[3] 

机构地区：[1]第三军医大学基础医学部数学教研室,重庆400038 [2]第三军医大学附属西南医院全军感染病研究所,重庆400038 [3]第三军医大学科研部生物波研究中心,重庆400038

出　　处：《第三军医大学学报》2003年第11期984-986,共3页Journal of Third Military Medical University

基　　金：国家自然科学基金资助项目 ( 10 10 10 2 9)

摘　　要：目的　探讨抗生素对竞争菌群失调的修复条件。方法　以两竞争菌群为研究对象 ,应用微分方程定性理论分析两竞争菌群的数学模型。结果　得到 3种不同类型的菌群失调及其修复条件。结论　对不同类型的菌群失调必须采用不同的修复方案 ,盲目地滥用抗生素达不到治疗效果。Objective To explore the conditions for the restoration of competitive dysbacteriosis with antibiotics. Methods The mathematical model of the two competitive floras was analyzed by the Qualitative Theory of Ordinary Differential Equations. Results Three different types of dysbacteriosis and their restoring conditions were obtained. Conclusion Different restoring schemes should be applied for the regulation of different types of dysbacteriosis. Misuse of antibiotics can not result in satisfactory therapeutic effect.

关 键 词：竞争 菌群失调 修复 数学模型 

分 类 号：R319[医药卫生—基础医学] R915