氮杂冠醚取代的单Schiff碱的合成及其钴(Ⅱ)配合物的氧加合性能  

Synthesis of Azacrown Ether-substituted Mono-Schiff Bases and Dioxygen Affinities of Their Co(Ⅱ) Complexes

作　　者：魏星跃[1] 毛治华[2] 李建章[1] 秦圣英[1] 

机构地区：[1]四川大学化学学院,成都610064 [2]四川大学分析测试中心,成都610064

出　　处：《化学学报》2004年第10期969-974,共6页Acta Chimica Sinica

基　　金：国家自然科学基金 (No.2 9572 0 50 )资助项目

摘　　要：由苯并 10 氮杂 15 冠 5出发 ,经 2～ 4步反应合成了氮杂冠醚取代的单Schiff碱HL1,HL2及其异构体HL3 ,HL4.并以元素分析 ,IR ,1 HNMR和MS进行了表征 .在不同温度下 ,测定了它们的钴 (Ⅱ )配合物的氧合反应平衡常数及热力学参数ΔH°和ΔS° ,并与合成的非冠醚类似物CoL2 5 ,CoL2 6和CoL2 7比较 。The azacrown ether substituted salicylaldimine mono Schiff bases HL1～HL4 were synthesized conveniently from benzo 10 aza 15 crown 5 via 2～4 reaction steps and characterized by IR, MS, 1H NMR and elemental analysis. Moreover, the oxygenation contants ( K O 2 ) and thermodynamic parameters (Δ H ° and Δ S °) of their cobalt(Ⅱ) complexes were determined in the range of -5 ℃ to 25 ℃. The effect of the substituted azacrown rings and their binding sites on dioxygen affinities of the cobalt(Ⅱ) complexes was also discussed as compared with that of crown free analogues CoL 25, CoL 26 and CoL 27.

关 键 词：苯并-10-氮杂-15-冠-5 单Schiff碱 钴配合物 氧合反应 生物体 氮杂冠醚 

分 类 号：O641.4[理学—物理化学]