多裂委陵菜化学成分的研究  

Studies on the chemical constituents from Potentilla multifida L.

作　　者：薛培凤[1] 乔梁[1] 梁鸿[1] 赵玉英[1] 

机构地区：[1]北京大学药学院天然药物化学研究室,北京100083

出　　处：《北京大学学报（医学版）》2004年第1期21-23,共3页Journal of Peking University:Health Sciences

摘　　要：目的 :研究多裂委陵菜 (PotentillamultifidaL )的化学成分。方法 :用色谱法和波谱法对多裂委陵菜的化学成分进行分离和结构鉴定。结果 :分离、鉴定了 5个化合物 :3β ,2 4 二羟基 乌苏 1 2 烯 (1 ) ;3β 羟基 乌苏 1 2 烯 2 8 酸 (2 ) ;2α ,3α,1 9α 三羟基 乌苏 1 2 烯 2 8 酸 (3) ;2α ,3β,1 9α 三羟基 乌苏 1 2 烯 2 8 酸 (4 ) ;3β,2 4 二羟基 齐墩果 1 2 烯 2 8 酸 (5 )。结论 :5个化合物均为首次从该种植物获得 ,1和 5为首次从该属植物获得 ,1为新天然产物。Objective: To study the chemical constituents of Potentilla multifida L. Methods: Chemical constituents were isolated by the repeated silica gel chromatography and Sephadex LH 20, and their structures were identified by the spectral analysis. Results: Five compounds were obtained as follows: 3β,24 dihydroxyl urs 12 ene (1), ursolic acid (2), euscaphic acid (3), tormentic acid (4), and epihedaragenin (5). Conclusion: Five compounds were isolated from this plant for the first time. Compounds 1 and 5 were isolated from this genus for the first time. Compound 1 was a new natural product.

关 键 词：多裂委陵菜 化学成分 色谱法 波谱法 结构鉴定 蔷薇科 

分 类 号：R282.71[医药卫生—中药学]