超声血管试验观察糖尿病患者收缩和舒张期频谱峰形态、数量及其变化的意义  

Peak shape,number and changes of systolic and diastolic blood spectrum in patients with diabetes mellitus

作　　者：黄云洲[1] 陈琳[2] 冯波[2] 

机构地区：[1]泰达国际心血管病医院超声科,天津300457 [2]同济大学附属东方医院内分泌科

出　　处：《中国医学影像技术》2004年第4期519-522,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的　简化糖尿病超声血管试验流程。方法　对包括单纯糖尿病亚组 (n =41)和血管硬化糖尿病亚组 (n =2 0 )的患者组 (n =61)和对照组 (n =17)进行内皮依赖性和非依赖性血管扩张试验。在基础状态、加压时、减压后和服药后 ,分别分析收缩和舒张期血流频谱峰数量、形态及其变化。结果　在基础状态 ,对照组和患者组舒张期血流频谱峰形态差别非常显著 (P <0 .0 0 1)。减压后 ,对照组、单纯糖尿病和血管硬化糖尿病组舒张期血流频谱峰形态差别非常显著 (P <0 .0 0 1)。减压后与加压时比较 ,对照组、单纯糖尿病和血管硬化糖尿病组舒张期血流频谱峰形态变化差别非常显著 (P <0 .0 0 1)。结论　在超声血管试验中 ,定性分析舒张期血流频谱峰形态及其变化即可评价糖尿病患者血流改变情况。Objective To predigest the procedure of vascular test with ultrasound in diabetes mellitus. Methods A test of endothelium-dependent and independent vasodilation was performed in 61 typeⅡdiabetes patents (patient group) including simple diabetes patients (simple diabetes subgroup, n =41) and diabetes patients with vascular atherosclerosis (diabetes with vascular atherosclerosis subgroup, n =20),and 17 control subjects (control group). The peak shape,number and changes of systolic and diastolic ultrasonic blood spectrum were analyzed respectively at baseline,pressurization,decompression,and post-nitroglycerin. Results There were significant differences between patient group and control group at baseline,among control group,simple diabetes subgroup,and diabetes with vascular atherosclerosis subgroup at decompression for the peak shape of diastolic spectrum and among control group,simple diabetes subgroup,and diabetes with vascular atherosclerosis subgroup for the peak shape changes of diastolic spectrum as decompression compared with pressurization (all P <0.001). Conclusion Qualitative analysis of the peak shape and changes of diastolic ultrasonic blood spectrum can evaluate diabetes and its blood flow change at vascular test with ultrasound in diabetes mellitus.

关 键 词：超声检查 糖尿病 硝酸甘油 

分 类 号：R587.1[医药卫生—内分泌] R445.2[医药卫生—内科学]