Combined-dynamic mode "dip-pen" nanolithography and physically nanopatterning along single DNA molecules  

作　　者：LIBin WANGYing WUHaiping ZHANGYi ZHANGZhixiang ZHOUXingfei LIMinqian HUJun 

机构地区：[1]ShanghaiInstituteofAppliedPhysics,ChineseAcademyofSciences.Shanghai201800,China [2]ShanghaiJiaotongUniversity,Bio-XScienceResearchCenter.Shanghai200030,China

出　　处：《Chinese Science Bulletin》2004年第7期665-667,共3页

摘　　要：Atomic force micriscope (AFM)-based dip-pen nanolithography (DPN) is an emerging approach for con-structing nanostructures on material surfaces such as gold, silicon and silicon oxide. Although DPN is a powerful tech-nique, it has not shown its ability of direct-writing and pat-terning of nanostructures on surfaces of soft materials, for example biomacromolecules. Direct depositing on soft sur-faces becomes possible with the introduction of a com-bined-dynamic mode DPN rather than mostly used contact mode DPN or tapping mode DPN. In this report, the com-bined dynamic mode DPN is used for direct depositing pro-tein ink on DNA molecules at the nanometer scale.Atomic force micriscope (AFM)-based dip-pen nanolithography (DPN) is an emerging approach for con-structing nanostructures on material surfaces such as gold, silicon and silicon oxide. Although DPN is a powerful tech-nique, it has not shown its ability of direct-writing and pat-terning of nanostructures on surfaces of soft materials, for example biomacromolecules. Direct depositing on soft sur-faces becomes possible with the introduction of a com-bined-dynamic mode DPN rather than mostly used contact mode DPN or tapping mode DPN. In this report, the com-bined dynamic mode DPN is used for direct depositing pro-tein ink on DNA molecules at the nanometer scale.

关 键 词：原子力显微镜 浸笔纳米光刻技术 单个DNA分子 纳米结构 材料表面 结合动力模型 纳米图案 

分 类 号：TB383[一般工业技术—材料科学与工程] TN305.7[电子电信—物理电子学]