抑肌素基因mRNA在猪肌肉组织表达差异的研究  

Study on mRNA Expression of Porcine Myostatin Gene in Muscular Tissues

作　　者：白素英[1] 刘娣 蒋国红[3] 杨秀琴[2] 

机构地区：[1]东北林业大学野生动物资源学院,哈尔滨150040 [2]东北农业大学动物科技学院,哈尔滨150030 [3]杭州动物园,杭州310008

出　　处：《畜牧兽医学报》2004年第3期350-352,共3页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：黑龙江省博士后科研基金资助项目(LRB00062)。

摘　　要：The myostatin gene, a member of the transforming growth factor-beta (TGF-β) surperfamily, is a negative regulatory factor of skeletal muscle growth. A series of experiments were carried out by the RT-PCR method to probe the difference of mRNA expression of porcine myostatin gene in three muscular tissues, namely skeletal muscle, heart muscle and stomach smooth muscle. mRNA expression was found in all muscular tissues. mRNA expression in skeletal muscle and heart muscle was more active than in the stomach smooth muscle. This discovery is of significance to getting further into the biological function of myostatin gene, and to directing the animal breeding at molecular level as well.The myostatin gene, a member of the transforming growth factor-beta (TGF-β) surperfamily, is a negative regulatory factor of skeletal muscle growth. A series of experiments were carried out by the RT-PCR method to probe the difference of mRNA expression of porcine myostatin gene in three muscular tissues, namely skeletal muscle, heart muscle and stomach smooth muscle. mRNA expression was found in all muscular tissues. mRNA expression in skeletal muscle and heart muscle was more active than in the stomach smooth muscle. This discovery is of significance to getting further into the biological function of myostatin gene, and to directing the animal breeding at molecular level as well.

关 键 词：抑肌素基因 MRNA 猪 肌肉组织 基因表达 RT—PCR 

分 类 号：S828.2[农业科学—畜牧学]