1,6-二磷酸果糖治疗新生儿缺氧缺血性脑病合并心肌损害疗效观察(英文)  

Observation of therapeutic effect of fructose-1,6-diphosphate in neonate hypoxic ischemic encephalopathy with myocardial injury

作　　者：李江林[1] 贺务实[1] 

机构地区：[1]暨南大学医学院第二附属医院,广东深圳518020

出　　处：《中国现代医学杂志》2004年第9期15-17,共3页China Journal of Modern Medicine

摘　　要：目的　探讨 1,6 -二磷酸果糖 (FDP)治疗新生儿缺氧缺血性脑病 (HIE)合并心肌损伤的疗效。方法　随机分成治疗组和对照组 ,均给予常规治疗 ,治疗组加用FDP 0 .2 5～ 0 .4g/ (kg·次 ) ,1次 /d静滴 ,10d为一疗程 ,治疗前后均进行心肌酶测定。结果　治疗组临床症状改善及心肌酶恢复效果均优于对照组 ,两组差异有显著性 (P <O .0 5 )。Objective: To observe the clinical effect of fructose-1,6-diphosphate (FDP) in neonate hypoxic ischemic encephalopathy (HIE) with myocardial injury.Methods: We treated 43 cases of neonate HIE with myocardial injury by routine treatment and fructose-1,6-diphosphate separately, then compared the time of recovery of clinical symptoms and heart enzymes.Results: There was a remarkable difference between them both in the recovery of clinical symptoms and heart enzymes. Conclusions: FDP is effective to treat both brain and myocardial injury of HIE.

关 键 词：1 6-二磷酸果糖 婴儿 新生缺氧缺血性脑病 心肌损伤 

分 类 号：R725.4[医药卫生—儿科]