利用DNA序列构建系统树的方法  

The Methods of Constructing Phylogenetic Trees with DNA sequences

作　　者：李涛[1] 赖旭龙[1] 钟扬[2] 

机构地区：[1]中国地质大学地球科学学院,武汉430074 [2]复旦大学生命科学学院,上海200433

出　　处：《遗传》2004年第2期205-210,共6页Hereditas（Beijing)

基　　金：国家自然科学基金项目(40172005)资助~~

摘　　要：利用DNA序列进行系统发生分析是分子进化研究的必要手段。构建系统树的方法有距离法、简约法、最大似然法以及贝叶斯推断法等。要解决特定的系统发生问题,首先要挑选合理的分类群及序列,尽量减少数据的偏倚,然后选择构树方法,最后还要对结果进行评价并给出进化学上的解释。通过讨论挑选数据的原则及存在的问题,介绍了几种构树方法的基本原理及步骤,并列举了它们的优缺点。Construction of phylogenetic trees is a key means in molecular evolutionary studies. The methods of constructing phylogenetic trees include the distance-based methods, parsimony, maximum likelihood, and Bayesian inference methods. To resolve a special problem about phylogeny, several notices are necessary: first, to select the reasonable data at less bias as possible; second, to choose the proper method to reconstruct phylogenetic tree; third, to evaluate the conclusions and explain them on the field of evolution. The present paper provides a brief introduction of the principles of data selection and tree-construction methods, and discusses about their advantage and disadvantage points.

关 键 词：DNA序列 系统树 分子进化 距离法 简约法 贝叶斯推断法 

分 类 号：Q11[生物学—普通生物学]