应用肺泡-动脉血氧分压差评估房间隔缺损肺内右向左分流  

EVALUATION OF INTRAPULMONARY SHUNT BY APPLICATION OF ALVEOLAR-ARTERIAL OXYGEN GRADIENT IN PATIENTS WITH ATRIAL SEPTAL DEFECT

作　　者：王宁夫[1] 陈长熙[1] 于润江[2] 

机构地区：[1]中国医科大学附属第一医院心脏科 [2]中国医科大学附属第一医院呼吸疾病研究所

出　　处：《中国医科大学学报》1992年第5期359-362,共4页Journal of China Medical University

摘　　要：作者以12例房间隔缺损患者研究,肺血流动力学对吸纯氧时肺泡-动脉血氧分压差(A-aDO_2)和肺泡-肺静脉血氧分压差(A-pvDO_2)的影响。房间隔缺损患者由于心内左向右分流,其动脉-混合静脉血氧含量差(c(a-V)O_2)明显缩小,但肺动脉压正常者(4例)肺内分流并不增大,而肺动脉高压者(8例),随着肺动脉压升高,吸纯氧时测得的A-aDO_2和A-pvDO_2进行性增大。Influences of pulmonary hemodynamies on alveolar-arterial oxygen gradient (A-aDO_2) and alveolar-pulmonary venous oxygen gradient (A-pvDO_2 during breathing pure oxygen were studied in 102 patients with atrial septal defect. Arterial-pulmonary arterial blood oxygen content difference (c (a-V)O_2) was remarkably diminished due to intra-cardiac left to right shunt in the patients with atrial septal defect.Intrapulmonary shunt was not increased in 4 patients with normal pulmonary artery pressure, but A-pvDO_2 and A-aDO_2 were progressively increased as pulmonary artery pressure increased in 8 patients with pulmonary hypertension.

关 键 词：室间隔缺损 肺动脉高压 

分 类 号：R541.102[医药卫生—心血管疾病]