皱纹盘鲍微卫星研究进展  

Advances in Studies on Microsatellite Markers in the Pacific Abalone

作　　者：李琪[1] 

机构地区：[1]中国海洋大学海水养殖教育部重点实验室,山东青岛266003

出　　处：《中国海洋大学学报（自然科学版）》2004年第3期365-370,共6页Periodical of Ocean University of China

基　　金：国家自然科学基金 ( 3 0 1 70 73 5 ) ;教育部留学回国人员科研启动基金资助

摘　　要：微卫星标记 (microsatellite markers)广泛分布于原核生物和真核生物基因组中 ,具有密度大、多态性丰富、遵循孟德尔分离定律共显性遗传、易于 PCR扩增等特点 ,已成为近年来最引人注目的新型 DNA标记。本文对皱纹盘鲍的微卫星标记的开发以及在种群遗传多样性评价、家系分析、人工苗种遗传变异监测研究方面的最新进展进行了综述 ,并阐述了微卫星标记在无效等位基因、大小承异同形性等方面存在的问题。Microsatellites are found in all prokaryotic and eukaryotic genomes. As they are evenly dispersed throughout genomes, usually characterized as codominant and highly polymorphic systems amenable to genotyping by polymerase chain reaction (PCR), and generally inherited in a Mendelian fashion, microsatellites have become instrumental as genetic markers in many areas. The paper summarizes the recent progress in microsatellites isolation and their applications in population study, parentage analysis, and detection of changes in genetic variation of farmed stocks, and reviews the problems of microsatellite markers including null alleles and size homoplasy.

关 键 词：皱纹盘鲍 微卫星标记 遗传变异 多态性 

分 类 号：Q959.212[生物学—动物学] Q75