吗啉胍同多十钒酸盐的自组装合成、结构表征及抗菌活性  

Self-assembly Synthesis,Structure Characterization and Antibacterial Activity of Complexes (ABOB)_4[H_2V_(10)O_(28)]·9H_2O and (ABOB)_6[V_(10)O_(28)] ·4H_2O(ABOB=Moroxydine)

作　　者：刘术侠[1] 翟宏菊[1] 彭军[1] 李德慧[1] 戴知旻[1] 王恩波[1] 胡宁海[2] 贾恒庆[2] 

机构地区：[1]东北师范大学化学学院,长春130024 [2]中国科学院长春应用化学研究所,长春130022

出　　处：《高等学校化学学报》2004年第6期997-1001,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 0 0 710 0 8);东北师范大学校内基金 (批准号 :1114 3 3 0 0 0 )资助

摘　　要：通过十钒酸盐与吗啉胍在不同 p H值水溶液中的自组装 ,合成了 2个新化合物 ( C6 H1 4N5O) 4·[H2 V1 0 O2 8]· 9H2 O( 1 )和 ( C6 H1 4N5O) 6 [V1 0 O2 8]· 4H2 O( 2 ) .通过 IR,51 V NMR和 X射线衍射等方法对其结构进行了表征 .结果表明 ,化合物 1和 2是通过十钒酸根阴离子与质子化的吗啉胍阳离子以静电力和氢键构筑的 ,多阴离子及吗啉胍的结构基本保持不变 .抗菌试验结果表明 ,两种化合物对金黄色葡萄球菌、表皮葡萄球菌、耐甲氧西林金黄葡萄球菌和耐甲氧西林表皮葡萄球菌均具有较强的抑制活性 .Two novel complexes(C_6H_ 14 N_5O)_4 [H_2V_ 10 O_ 28 ] ·9H_2O(1) and (C_6H_ 14 N_5O)_6 [V_ 10 O_ 28 ] ·4H_2O(2) were synthesized by the self-assembly of decavanadate and ABOB in aqueous medium at different pH values for the first time. Their structures were determined by means of IR, 51 V NMR and X-ray diffraction. Complex 1 crystallizes in the monoclinic system,space group P2_1/c with a= 1.339 58(8) nm ,b=1\^482 62(9) nm,c=1.713 53(14) nm,β=111.450(3)°,V=3.167 5(4) nm 3,Z=2,R_1=0.050 0,wR_2=0.143 4. Complex 2 crystallizes in the monoclinic system,space group P2_1/n with a=11.698 8(7) nm,b=2.407 94(11) nm,c=1.313 20(10) nm,β=91.635(2)°,V=3.697 8(4) nm 3,Z=2,R_1=0\^039 7,wR_2=0.100 8. The X-ray crystallographic study shows that the crystals are constructed by electrostatic forces and hydrogen bond interactions among decavanadate anions,protonated ABOB cations and lattice water molecules. The polyanions,cations and water molecules arrayed in a good order to form 2D layered arrangements along the c axis in complex 1. The antibacterial trial shows that the two complexes show an good antibacterial activity against Staphylococcus aureus,Staphylococcus epidermis,MRSA and MRSE.

关 键 词：十钒酸盐 吗啉胍 自组装 合成 抗菌活性 

分 类 号：O614[理学—无机化学]