抗精子抗体与不孕不育症及习惯性流产的关系  

Antisperm antibody in relation to Infertility and habitual abortion

作　　者：张文浩[1] 黎玥 苏心[1] 

机构地区：[1]天津市计划生育研究所,邮政编码300191

出　　处：《生殖医学杂志》1992年第2期85-88,共4页Journal of Reproductive Medicine

摘　　要：报道了近3年来我们对正常人、不孕不育症和习惯性流产患者的抗精子抗体的检测情况。结果发现:41名正常男性抗精子抗体均为阴性;初次来我所进行抗精子抗体检测的676名男女不孕不育症患者中,约16％的男性患者和29％的女性患者体内有抗精子抗体;其中276对不孕症夫妇,双方均为抗精子抗体阳性的约占8％,仅女方抗体阳性的约占20％,仅男方抗体阳性的约占7％。女方抗精子抗体发生率较男方为高,强阳性者也较多。结果表明抗精子抗体等免疫学因素确实是不孕症的病因之一。另外对162对习惯性流产患者及其丈夫进行了抗精子抗体检测,结果发现约2％的患者和12％患者的丈夫体内有抗精子抗体。但是与不孕症患者相比,习惯性流产患者中抗精子抗体强阳性者明显减少。In the present studies,the results of antisperm antibody levels in normal men,infertile or habitual abortion patients during the last 3 years are reported. In our study,the sera and semen samples from 41 normal men,676 infertile patients and 162 habitual abortion patients and their husbands were tested.The test used was immunobead binding test.There was complete absence of positive test in normal male group.In the infertile group,about 16% male patients (n=369) and 29% female patients(n=307) were positive.Among 276 infertile couples,8% of both husband and wife had antisperm antibody,20% of on- ly wife and 70% of only husband had antisperm anti- body.In habitual abortion group,26% of patients(n =87) and 12% of patients' husbands(n=75) showed positive results.Comparing with the infertile group,the antibody titer in the abortion group was much lower.

关 键 词：习惯性流产 女性不育 抗精子抗体 

分 类 号：R711.602[医药卫生—妇产科学] R714.210.2[医药卫生—临床医学]