记忆合金网二期成形人工气管实验研究  

Experimental study of replacement of artificial tracheal prosthesis by two-stage procedure with memory-alloy mesh

作　　者：张银合[1] 赵凤瑞[1] 刘德若[1] 宋之乙[1] 陈京宇[1] 辛育龄[1] 

机构地区：[1]中国协和医科大学中日友好医院胸外科

出　　处：《中华胸心血管外科杂志》2004年第2期67-69,共3页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：目的　寻找一种能与自体气管完全愈合为一体的人工气管。方法　将 2 0只犬随机分为带蒂组和不带蒂组 ,经二期手术成形制成“三明治”式人工气管。置换 6cm长颈部气管 ,观察其生存期、吻合口有无狭窄等。结果　带蒂组术后除 1只出现吻合口狭窄 ,2只出现吻合口感染外 ,其余 7只生活质量好。不带蒂组犬术后 4周内全部死于吻合口狭窄和感染。结论　带蒂记忆合金网二期成形人工气管基本可与自体气管融为一体 ,成为自体气管的一部分。此种人工气管可以应用到临床。Objective: To make an artificial trachea, which can really healed with native trachea. Methods: 20 dogs are randomized into a pedicle group and a nonpedicle group. 6 cm cervical trachea was resected and replaced with 'sandwich' artificial trachea made from memory alloy meshes by two-stage operative procedure. Survival period and stenosis of anastomosis were recorded. Results: Seven dogs in pedicle group survived well and another three were dead. The cause of death was anastomosis stricture in 1 and infection in 2. All dogs in nonpedicle group were dead within four weeks because of stenosis or infection. Conclusion: Two-stage operative pedicle 'sandwich' artificial trachea made from memory alloy mesh is up to now the closest artificial trachea to human native trachea. It could be applied clinically.

关 键 词：记忆合金网 二期 人工气管 实验 气管重建 气管疾病 生物假体 

分 类 号：R318.1[医药卫生—生物医学工程]