食盐加碘对轻度碘缺乏地区住院甲状腺疾病谱的影响  

Retrospective study on thyroid diseases after universal salt iodization in mild iodine deficiency area

作　　者：吴民义[1] 张建伟[1] 赵金扣[1] 张庆兰[1] 谢轶青[1] 杨明霞[1] 冷瑞珍[1] 

机构地区：[1]常州市疾病预防控制中心,213003

出　　处：《中华内分泌代谢杂志》2004年第2期104-106,共3页Chinese Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金资助项目 (30 2 30 330 );江苏省血地寄防科研基金 (2 0 0 0 1 9)

摘　　要：目的　研究全民食盐加碘 (USI)对住院甲状腺疾病谱的影响。方法　采用回顾性调查方法查阅甲状腺疾病住院病史。结果　USI实施 1～ 4年甲状腺疾病占总住院比例呈逐渐升高趋势 ,由 7.6‰升高到 11.0‰ ;男 /女比例由 1:3 .6升到 1:4.1;<2 0岁组比例由 2 .5 %上升到 3 .4% ;甲状腺良性肿瘤由 48.5 %下降到 3 8.5 % ,甲状腺功能亢进症由 2 7.1%上升到 3 7.2 %。实施USI后居民食盐碘含量和尿碘中位数分别由 <5mg/kg和 72 μg/L上升到 48mg/kg和 3 75 μg/L。 结论　住院甲状腺疾病的增加可能与USI的实施使碘营养状态急速改善有关。可适当降低食盐加碘量 ,使之达到推荐碘摄入水平。Objective To investigate the effect of universal salt iodization (USI) on the profile of in-patient thyroid diseases. Methods Informations on thyroid diseases were collected by retrospective approach in hospitalized patients. Results With USI for 1-4 years, the incidence of thyroid diseases in the total in-patient cases increased from 7.6‰ to 11.0‰, the female/male ratio increased from 3.6 to 4.1, patients aged<20 years old increased from 2.5% to 3.4%, benign thyroid tumors dropped from 48.5% to 38.5%, while cases with hyperthyroidism increased from 27.1% to 37.2%. With USI, iodine content of diet salt and the urinary iodine median were raised respectively from <5 mg/kg to 48 mg/kg and from 72 μg/L to 375 μg/L. Conclusion The increased incidence of in-patient thyroid diseases may be associated with the rapid increase of iodine intake in the population. The amount of iodine added to salt could be appropriately reduced to ensure optimal iodine intake.

关 键 词：食盐加碘 碘缺乏地区 甲状腺疾病 流行病学 

分 类 号：R581[医药卫生—内分泌]