自动听性脑干反应技术在高危新生儿听力筛查中的探索性研究  

The exploratory study of auto-auditory brainstem response in the high-risk infants on hearing screening

作　　者：亓贝尔[1] 戚以胜[1] 聂文英[2] 相丽丽[2] 

机构地区：[1]首都医科大学附属北京同仁医院北京市耳鼻咽喉科研究所,100005 [2]济南市妇幼保健院新生儿听力筛查康复中心

出　　处：《中华医学杂志》2004年第2期115-118,共4页National Medical Journal of China

基　　金：国家自然科学基金资助项目 (3 0 10 0 2 0 7)

摘　　要：目的　比较儿科临床中不同高危因素对自动听性脑干反应 (AABR)通过率的影响。方法　应用瞬态诱发性耳声发射 (TEOAE)及AABR技术对 2 4 5名 (488耳 )早产、低出生体重、高胆红素血症、窒息及肺部疾病等高危因素的新生儿进行测试。结果　同一高危因素下两种筛查方法的结果不同。“通过”TEOAE而“未通过”AABR测试的早产新生儿 15耳 ,足月小样儿 3耳 ,高胆红素血症新生儿 1耳 ,窒息新生儿 5耳 ,肺部疾病新生儿 35耳。肺部疾病患儿合并其他高危因素时 ,AABR通过率较单纯肺部疾病者低 ,差异有显著性意义 (χ2 =35 .72 3,P <0 .0 1)。不同高危因素的患儿之间 ,AABR测试的通过率差异有显著性意义 (χ2 =4 0 .5 5 6 ,P <0 .0 1)。结论　在高危因素的影响下 ,其患儿AABR“未通过”率升高 ,表明临床中高危因素对听觉功能具有一定影响 ,在听力筛查中应给予高度重视。Objective To compare the pass rate of auto-auditory brainstem response (AABR) in infants complicated with different high-risk factors. Methods 245 infants(488 ears) with different high-risk factors, including premature, low-weight, hyperbilirubinemia, asphyxiation and pulmonary diseases,were tested by transiently evoked otoacoustic emission (TEOAE) and AABR at the same time. Results The pass rate of AABR and that of TEOAE were different for the infants with different high-risk factors. The number that passed TEOAE test and referred to AABR test: premature 15 ears, low-weight 3 ears, for hyperbilirubinemia 1 ears, for asphyxiation 5 ears, and for pulmonary diseases 35ears. The pass rate of AABR was reduced evidently when infants had pulmonary diseases and the complicated high-risk factors(χ~2=35.723, P <0.01).Different high-risk factors produced different pass rates of AABR (χ~2=40.556, P <0.01). Conclusion High-risk factors effect the auditory function.The pass rate of AABR is reduced evidently when an infant has both pulmonary diseases and the complicated high-risk factors. We should pay attention to these infants in universal newborn hearing screening.

关 键 词：自动听性脑干反应技术 高危新生儿 听力筛查 瞬态诱发性耳声发射 诊断标准 

分 类 号：R764[医药卫生—耳鼻咽喉科]